剪切的 Notch1 (Val1744) (D3B8) 兔单克隆抗体 Cleaved Notch1 (Val1744) (D3B8) Rabbit mAb

剪切的 Notch1 (Val1744) (D3B8) 兔单克隆抗体

Cleaved Notch1 (Val1744) (D3B8) Rabbit mAb

详细描述:
剪切的Notch1 (Val1744) (D3B8)Rabbit mAb兔单抗只识别甘氨酸1743和缬氨酸1744倍剪切的内源性Notch1 蛋白的胞质结构域。此抗体不识别全长Notch1或Notch1其他位置剪切型Notch1。不同细胞系会存在Notch1远端羧基末端的突变,因此导致抗体检测不同大小的剪切型Notch1(见参考文献6和7).单克隆抗体是通过一种合成的肽段去免疫动物产生。这种合成的肽段与邻近人源Notch1蛋白的Val1744剪切点的氨基酸残基序列一致。Cleaved Notch1 (Val1744) (D3B8) Rabbit mAb detects endogenous levels of the cytosolic domain of Notch1 only when cleaved between Gly1743 and Val1744. The antibody does not recognize full length Notch1 or Notch1 cleaved at other positions. It detects Cleaved Notch1 with different sizes in different cell lines due to mutations at the distant C-termini of Notch1 (see refs 6 and 7).Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence at the Val1744 cleavage site of human Notch1.

应用范围:W IP ChIP; 反应种属:Human,Mouse,Rat; 灵敏度:Endogenous; MW (kDa):110; Isotype:Rabbit IgG; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
4147T 剪切的 Notch1 (Val1744) (D3B8) 兔单克隆抗体 20 µl 咨询客服
4147S 剪切的 Notch1 (Val1744) (D3B8) 兔单克隆抗体 100µl 咨询客服

Notch1 (D6F11) XP® 兔单克隆抗体 Notch1 (D6F11) XP® Rabbit mAb

Notch1 (D6F11) XP® 兔单克隆抗体

Notch1 (D6F11) XP® Rabbit mAb

详细描述:
Notch1 (D6F11) XP® Rabbit可以识别内源的总notch1蛋白。它能够识别Notch1的全长蛋白(~300 kDa)和跨膜/细胞内结构NTM(~120 kDa)。合成与人源notch蛋白的Gln2497氨基酸残基序列一致的肽段,免疫动物获得单克隆抗体。Notch1 (D6F11) XP® Rabbit detects endogenous level of total notch1 protein. It recognizes both the full-length (~300 kDa) and the transmembrane/intracellular region NTM (~120 kDa).Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln2497 of human notch1.

应用范围:W F IF-IC; 反应种属:Human,Mouse,Rat; 灵敏度:Endogenous; MW (kDa):120, 300; Isotype:Rabbit IgG; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
4380T Notch1 (D6F11) XP® 兔单克隆抗体 20 µl 咨询客服
4380S Notch1 (D6F11) XP® 兔单克隆抗体 100µl 咨询客服

Notch2 (D67C8) XP® 兔单克隆抗体 Notch2 (D67C8) XP® Rabbit mAb

Notch2 (D67C8) XP® 兔单克隆抗体

Notch2 (D67C8) XP® Rabbit mAb

详细描述:
Notch2 (D67C8) XP® Rabbit mAb兔单抗识别内源性的总Notch2 蛋白,它识别Notch2 的全长(~300kDa)蛋白和跨膜胞内区域NTM (~110 kDa)。单克隆抗体是通过一种合成的肽段去免疫动物产生。这种合成的肽段与邻近人源Notch2蛋白的Val2332氨基酸残基序列一致。Notch2 (D67C8) XP® Rabbit mAb detects endogenous levels of total Notch2 protein. It recognizes both the full-length (~ 300 kDa) and the transmembrane/intracellular region NTM (~110 kDa).Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding residues surrounding Val2332 of human Notch2.

应用范围:W IP IF-IC; 反应种属:Human,Rat; 灵敏度:Endogenous; MW (kDa):110, 300; Isotype: Rabbit IgG; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
4530T Notch2 (D67C8) XP® 兔单克隆抗体 20 µl 咨询客服
4530S Notch2 (D67C8) XP® 兔单克隆抗体 100µl 咨询客服

Notch3 (D11B8) 兔单克隆抗体 Notch3 (D11B8) Rabbit mAb

Notch3 (D11B8) 兔单克隆抗体

Notch3 (D11B8) Rabbit mAb

详细描述:
Notch3 (D11B8)Rabbit mAb识别内源性的总Notch3蛋白。此抗体可以识别Notch3的270 kDa的全长蛋白(FL)和90 kDa的截短蛋白(NTM),这个截短蛋白包含一个短的胞外结构,跨膜区域和胞内区域。合成与人Notch3蛋白邻近Glu2312氨基酸残基序列一致的肽段,免疫动物获得单克隆抗体。Notch3 (D11B8) Rabbit mAb detects endogenous levels of total Notch3 protein. The antibody recognizes both full-length (FL) Notch3 at 270 kDa and a truncated protein (NTM) containing a short extracellular region, the transmembrane domain and the intracellular region at 90 kDa.Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Glu2312 of human Notch3 protein.

应用范围:W IP; 反应种属:Human; 灵敏度:Endogenous; MW (kDa):90, 270; Isotype:Rabbit IgG; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
5276T Notch3 (D11B8) 兔单克隆抗体 20 µl 商城订购
5276S Notch3 (D11B8) 兔单克隆抗体 100µl 商城订购

Notch2 (D76A6) XP® 兔单克隆抗体 Notch2 (D76A6) XP® Rabbit mAb 

Notch2 (D76A6) XP® 兔单克隆抗体

Notch2 (D76A6) XP® Rabbit mAb 

详细描述:
Notch2 (D76A6) XP® 兔单抗识别内源性的Notch2蛋白。单克隆抗体是通过一种合成的肽段去免疫动物产生。这种合成的肽段与邻近人源Notch2蛋白的Ala2378氨基酸残基序列一致。Notch2 (D76A6) XP® Rabbit mAb recognizes endogenous levels of total Notch2 protein.Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala2378 of human Notch2 protein.

应用范围:W IP F IF-IC; 反应种属:Human,Mouse,Rat; 灵敏度:Endogenous; MW (kDa):110, 300; Isotype:Rabbit; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
5732T Notch2 (D76A6) XP® 兔单克隆抗体 20 µl 商城订购
5732S Notch2 (D76A6) XP® 兔单克隆抗体 100µl 商城订购

Notch1 (D6F11) XP® 兔单克隆抗体 (PE 偶联) Notch1 (D6F11) XP® Rabbit mAb (PE Conjugate)

Notch1 (D6F11) XP® 兔单克隆抗体 (PE 偶联)

Notch1 (D6F11) XP® Rabbit mAb (PE Conjugate)

详细描述:
Notch1 (D6F11) XP® Rabbit mAb (PE Conjugate) recognizes intracellular epitopes between 2400 and 2500 amino acids of human Notch1 protein. It recognizes both the full-length (~300 KDa) and the NTM region (~120 KDa), which consists of a short extracellular juxtamembrane peptide, a transmembrane sequence, and the intracellular domain (NICD). The antibody cannot detect the extracellular (ligand-binding) domain of Notch1 following cleavage at the S2 site by ADAM-type metalloproteases.This Cell Signaling Technology antibody is conjugated to phycoerythrin (PE) and tested in-house for direct flow cytometry analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Notch1 (D6F11) XP® Rabbit mAb #4380.

应用范围:F; 反应种属:Human,Mouse,Rat; 灵敏度:Endogenous;Isotype:Rabbit IgG; 标记:PE。

货号 产品名称 品牌 购买
货号 名称 单位 购买
15004S Notch1 (D6F11) XP® 兔单克隆抗体 (PE 偶联) 100µl 咨询客服

Notch2 (8A1) 兔单克隆抗体 Notch2 (8A1) Rabbit mAb

Notch2 (8A1) 兔单克隆抗体

Notch2 (8A1) Rabbit mAb

详细描述:
Notch2 (8A1)Rabbit mAb兔单抗识别内源的总Notch2 蛋白. 此单抗由重组蛋白免疫动物产生,该重组蛋白包含人源Notch2蛋白的异源二聚体结构域. Notch2 (8A1) Rabbit mAb detects endogenous levels of total Notch2 protein. Monoclonal antibody is produced by immunizing animals with a recombinant protein consisting of the heterodimerization domain of human Notch2.

应用范围:W IP; 反应种属:Human; 灵敏度:Endogenous; MW (kDa):230, 300; Isotype:Rabbit IgG; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
2420S Notch2 (8A1) 兔单克隆抗体 100µl 咨询客服

Notch4 (L5C5) 小鼠单克隆抗体 Notch4 (L5C5) Mouse mAb

Notch4 (L5C5) 小鼠单克隆抗体

Notch4 (L5C5) Mouse mAb

详细描述:
Notch4 (L5C5)Mouse mAb小鼠单抗识别转染水平的人Notch4蛋白的胞内区域. 单抗由重组蛋白免疫动物产生,该重组蛋白包含人源Notch4蛋白的锚蛋白复制结构域。Notch4 (L5C5) Mouse mAb detects levels of the transfected intracellular region of human Notch4 protein. Monoclonal antibody is produced by immunizing animals with a recombinant protein consisting of the Ankyrin repeat domain of human Notch4.

应用范围:W IP; 反应种属:Human; 灵敏度:Transfected Only; MW (kDa):80 cleaved. 230 full-length.; Isotype:Mouse IgG1; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
2423S Notch4 (L5C5) 小鼠单克隆抗体 100µl 咨询客服

剪切的 Notch1 (Val1744) (D3B8) 兔单克隆抗体 Cleaved Notch1 (Val1744) (D3B8) Rabbit mAb

剪切的 Notch1 (Val1744) (D3B8) 兔单克隆抗体

Cleaved Notch1 (Val1744) (D3B8) Rabbit mAb

详细描述:
剪切的Notch1 (Val1744) (D3B8)Rabbit mAb兔单抗只识别甘氨酸1743和缬氨酸1744倍剪切的内源性Notch1 蛋白的胞质结构域。此抗体不识别全长Notch1或Notch1其他位置剪切型Notch1。不同细胞系会存在Notch1远端羧基末端的突变,因此导致抗体检测不同大小的剪切型Notch1(见参考文献6和7).单克隆抗体是通过一种合成的肽段去免疫动物产生。这种合成的肽段与邻近人源Notch1蛋白的Val1744剪切点的氨基酸残基序列一致。Cleaved Notch1 (Val1744) (D3B8) Rabbit mAb detects endogenous levels of the cytosolic domain of Notch1 only when cleaved between Gly1743 and Val1744. The antibody does not recognize full length Notch1 or Notch1 cleaved at other positions. It detects Cleaved Notch1 with different sizes in different cell lines due to mutations at the distant C-termini of Notch1 (see refs 6 and 7).Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence at the Val1744 cleavage site of human Notch1.

应用范围:W IP ChIP; 反应种属:Human,Mouse,Rat; 灵敏度:Endogenous; MW (kDa):110; Isotype:Rabbit IgG; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
4147T 剪切的 Notch1 (Val1744) (D3B8) 兔单克隆抗体 20 µl 咨询客服
4147S 剪切的 Notch1 (Val1744) (D3B8) 兔单克隆抗体 100µl 咨询客服

Notch1 (D6F11) XP® 兔单克隆抗体 Notch1 (D6F11) XP® Rabbit mAb

Notch1 (D6F11) XP® 兔单克隆抗体

Notch1 (D6F11) XP® Rabbit mAb

详细描述:
Notch1 (D6F11) XP® Rabbit可以识别内源的总notch1蛋白。它能够识别Notch1的全长蛋白(~300 kDa)和跨膜/细胞内结构NTM(~120 kDa)。合成与人源notch蛋白的Gln2497氨基酸残基序列一致的肽段,免疫动物获得单克隆抗体。Notch1 (D6F11) XP® Rabbit detects endogenous level of total notch1 protein. It recognizes both the full-length (~300 kDa) and the transmembrane/intracellular region NTM (~120 kDa).Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln2497 of human notch1.

应用范围:W F IF-IC; 反应种属:Human,Mouse,Rat; 灵敏度:Endogenous; MW (kDa):120, 300; Isotype:Rabbit IgG; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
4380T Notch1 (D6F11) XP® 兔单克隆抗体 20 µl 咨询客服
4380S Notch1 (D6F11) XP® 兔单克隆抗体 100µl 咨询客服

Notch2 (D67C8) XP® 兔单克隆抗体 Notch2 (D67C8) XP® Rabbit mAb

Notch2 (D67C8) XP® 兔单克隆抗体

Notch2 (D67C8) XP® Rabbit mAb

详细描述:
Notch2 (D67C8) XP® Rabbit mAb兔单抗识别内源性的总Notch2 蛋白,它识别Notch2 的全长(~300kDa)蛋白和跨膜胞内区域NTM (~110 kDa)。单克隆抗体是通过一种合成的肽段去免疫动物产生。这种合成的肽段与邻近人源Notch2蛋白的Val2332氨基酸残基序列一致。Notch2 (D67C8) XP® Rabbit mAb detects endogenous levels of total Notch2 protein. It recognizes both the full-length (~ 300 kDa) and the transmembrane/intracellular region NTM (~110 kDa).Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding residues surrounding Val2332 of human Notch2.

应用范围:W IP IF-IC; 反应种属:Human,Rat; 灵敏度:Endogenous; MW (kDa):110, 300; Isotype: Rabbit IgG; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
4530T Notch2 (D67C8) XP® 兔单克隆抗体 20 µl 咨询客服
4530S Notch2 (D67C8) XP® 兔单克隆抗体 100µl 咨询客服

Notch3 (D11B8) 兔单克隆抗体 Notch3 (D11B8) Rabbit mAb

Notch3 (D11B8) 兔单克隆抗体

Notch3 (D11B8) Rabbit mAb

详细描述:
Notch3 (D11B8)Rabbit mAb识别内源性的总Notch3蛋白。此抗体可以识别Notch3的270 kDa的全长蛋白(FL)和90 kDa的截短蛋白(NTM),这个截短蛋白包含一个短的胞外结构,跨膜区域和胞内区域。合成与人Notch3蛋白邻近Glu2312氨基酸残基序列一致的肽段,免疫动物获得单克隆抗体。Notch3 (D11B8) Rabbit mAb detects endogenous levels of total Notch3 protein. The antibody recognizes both full-length (FL) Notch3 at 270 kDa and a truncated protein (NTM) containing a short extracellular region, the transmembrane domain and the intracellular region at 90 kDa.Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Glu2312 of human Notch3 protein.

应用范围:W IP; 反应种属:Human; 灵敏度:Endogenous; MW (kDa):90, 270; Isotype:Rabbit IgG; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
5276T Notch3 (D11B8) 兔单克隆抗体 20 µl 咨询客服
5276S Notch3 (D11B8) 兔单克隆抗体 100µl 咨询客服

Notch2 (D76A6) XP® 兔单克隆抗体 Notch2 (D76A6) XP® Rabbit mAb

Notch2 (D76A6) XP® 兔单克隆抗体

Notch2 (D76A6) XP® Rabbit mAb

详细描述:
Notch2 (D76A6) XP® 兔单抗识别内源性的Notch2蛋白。单克隆抗体是通过一种合成的肽段去免疫动物产生。这种合成的肽段与邻近人源Notch2蛋白的Ala2378氨基酸残基序列一致。Notch2 (D76A6) XP® Rabbit mAb recognizes endogenous levels of total Notch2 protein.Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala2378 of human Notch2 protein.

应用范围:W IP F IF-IC; 反应种属:Human,Mouse,Rat; 灵敏度:Endogenous; MW (kDa):110, 300; Isotype:Rabbit; 标记:无标记。

货号 产品名称 品牌 购买
货号 名称 单位 购买
5732T Notch2 (D76A6) XP® 兔单克隆抗体 20 µl 咨询客服
5732S Notch2 (D76A6) XP® 兔单克隆抗体 100µl 咨询客服