Harlan TD.95027低钙饲料(0.4%P)

Harlan TD.95027低钙饲料(0.4%P)
Harlan货号:TD.95027
英文名称:Low Calcium Diet (0.4% P)
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Formula                                                                     g/Kg
Casein                                                                    200.0
Cystine                                                                     3.0
Sucrose                                                            342.188
Corn Starch                                                         320.0
Soybean Oil                                                          60.0
Cellulose                                                              40.0
Mineral Mix, Ca-P Deficient (79055)                    13.37
Potassium Phosphate, monobasic                     11.43
Vitamin Mix, Teklad (40060)                                10.0
Ethoxyquin, antioxidant                                       0.012
Key Features
+ Purified Diet
+ Calcium
+ Phosphorus
Key Planning Information
+ Products are made fresh to order
+Store product at 4°C or lower
+Use within 6 months (applicable to most diets)
+Box labeled with product name, manufacturing date, and lot number
+ Replace diet at minimum once per week More frequent replacement may be advised
+ Lead time:
· 2 weeks non-irradiated
· 4 weeks irradiated
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Harlan 动脉粥样硬化(胆固醇、脂肪、胆酸盐) 饲料Atherogenic

Harlan 动脉粥样硬化(胆固醇、脂肪、胆酸盐) 饲料Atherogenic
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Harlan 动脉粥样硬化(胆固醇、脂肪、胆酸盐) 饲料Atherogenic
Atherogenic

Research use Key dietary features Examples
“Western” purified atherogenic diet
Accelerated hypercholesterolemia and plaque formation in genetically modified models such as Apoe and Ldlr deficient mice.
Used for diet induced obesity in a variety of rodent models.
High fat diet (20 – 23% by weight; 40 – 45% kcal from fat)
Saturated fatty acids (SFA >60% of total fatty acids)
Milkfat/butterfat
Sucrose (34% by weight)
Cholesterol (0.2% total)
TD.88137
TD.10885
“Western” purified atherogenic diet with added cholesterol and cholate source*
Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) in primarily wild type mice and rats.
Will not promote obesity.
High fat diet (15 – 20% by weight; 34 – 45% kcal from fat)
Saturated fatty acids (SFA >55% of total fatty acids)
Milkfat/butterfat, cocoa butter
Sucrose (30-50% by weight)
Cholesterol (1 – 1.25%)
Cholate Source (0.5%)*
TD.02028
TD.09237
Hybrid high fat diets with added cholesterol and cholate source*
Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) in primarily wild type mice and rats.
Will not promote obesity.
Also used for lithogenic (gallstone) rodent studies.
75% rodent breeder diet; 25% purified ingredients
High fat (~15% by weight; 37% kcal from fat)
Saturated fatty acids (SFA >45% of total fatty acids)
Cholesterol (1.25%)
Cholate source (0.5%)*
TD.88051
TD.90221
Standard diets with added cholesterol
Induce hypercholesterolemia in genetically modified and wild type models without promoting obesity. Standard, grain-based rodent diet
Minimal/moderate phytoestrogen diets recommended
Cholesterol (1 – 4%)
TD.120097
TD.07841
TD.01383

*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis. However, if including a cholate source is not desired for your research, diets without cholate are available.
*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis.However, if including a cholate source is not desired for your research, diets without cholate are available.

在实验动物模型中,饮食是诱导或加速动脉粥样硬化的有用工具。用于诱发啮齿类动物动脉粥样硬化的主要饮食特征因研究模型、所需终点和喂养时间的不同而不同。尽管动脉粥样硬化饮食的配方在不断发展,但文献中详细描述的备选方案概述如下。有关每个饮食选项和文献参考的更多信息,请参见节目表后面的可扩展选项卡。
研究用途 主要饮食特征 实例
“西方”纯正致动脉粥样硬化饮食
加速高胆固醇血症和斑块形成的转基因模型,如APOE和Ldlr缺乏的小鼠。
用于饮食诱导肥胖的各种啮齿动物模型。
  • 高脂饮食(按体重计算占20-23%;脂肪占40-45%)
  • 饱和脂肪酸(SFA>总脂肪酸的60%)
  • 乳脂/乳脂
  • 蔗糖(按重量计占34%)
  • 胆固醇(总数0.2%)
TD.88137
TD.10885
添加胆固醇和胆酸来源的“西方”纯动脉粥样硬化饮食*
在野生型小鼠和大鼠中诱导高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。
不会助长肥胖。
  • 高脂饮食(体重15-20%;脂肪34-45千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的55%)
  • 乳脂/黄油、可可脂
  • 蔗糖(重量占30%-50%)
  • 胆固醇(1-1.25%)
  • 巧克力来源(0.5%)*
TD.02028
TD.09237
添加胆固醇和胆酸盐的混合高脂饮食*
在野生型小鼠和大鼠中诱导高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。
不会助长肥胖。
也用于造石(胆石)啮齿动物的研究。
  • 75%的啮齿动物饲养员;25%的纯化成分
  • 高脂肪(体重约15%;脂肪37%千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的45%)
  • 胆固醇(1.25%)
  • 巧克力源(0.5%)*
TD.88051
TD.90221
添加胆固醇的标准饮食
在转基因和野生型模型中诱导高胆固醇血症而不促进肥胖。
  • 标准的、以谷物为基础的啮齿动物饮食
  • 最小/中度植物雌激素饮食建议
  • 胆固醇(1-4%)
TD.120097
TD.07841
TD.01383

*胆酸钠或胆酸有助胆固醇和脂肪的吸收,并可透过胆汁酸合成减少胆固醇的排出。然而,如果你的研究不想包括胆酸盐的来源,没有胆酸盐的饮食是可用的。

“Western” purified atherogenic diet
“Western” style diets are fed to genetically-modified cardiovascular models, such as Apoe and Ldlr deficient mice, to accelerate and enhance hypercholesterolemia and plaque formation and to elicit phenotypes commonly associated with metabolic syndrome.Within the atherogenic literature, a “Western” diet typically is described as a purified rodent diet with 20-23% milkfat/butterfat, 0.2% total cholesterol, and 34% sucrose by weight.TD.88137is an example of a “Western” style diet that was originally designed to characterize and enhance atherosclerosis development in a newly generated Apoe-deficient mouse model.Contact us for more information about “Western” style diets, modifications, or possible control diets.
Examples:
TD.88137Adjusted calories diet (42% from fat, 0.2% total cholesterol)
TD.1088545% fat Kcal diet (0.2% total cholesterol)
Research use:
Accelerated hypercholesterolemia and plaque formation in genetically-modified models, such as Apoe and Ldlr deficient mice.
Used for diet-induced obesity in a variety of rodent models.
Key dietary features:
High Fat Diet (20-23% by weight; 40 – 45% kcal from fat)
Saturated fatty acids (SFA >60% of total fatty acids)
Milkfat/butterfat
Sucrose (34% by weight)
Cholesterol (0.2% total)
References:
1.Febbraio, M., et al., Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice.J Clin Invest, 2000.105(8): p.1049-56.
2.Huszar, D., et al., Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1.Arterioscler Thromb Vasc Biol, 2000.20(4): p.1068-73.
3.Nakashima, Y., et al., ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.Arterioscler Thromb, 1994.14(1): p.133-40.
4.Nakashima, Y., et al., Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse.Arterioscler Thromb Vasc Biol, 1998.18(5): p.842-51.
5.Plump, A.S., et al., Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells.Cell, 1992.71(2): p.343-53.
6.Towler, D.A., et al., Diet-induced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice.J Biol Chem, 1998.273(46): p.30427-34.
7,Tsuchiya, K., et al., FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis.Cell Metab, 2012.15(3): p.372-81.
“Western” purified atherogenic diet with added cholesterol and cholate source*
Wild type mice and rats generally are resistant to atherosclerosis, requiring more extreme dietary manipulation to modify lipoprotein profiles and develop mild atherosclerosis (foam cells, fatty streaks).Modern formulations are made completely of purified ingredients because this more refined approach has been reported to decrease the incidence of gallstones and liver damage associated with less refined and more traditional dietary approaches.To induce mild atherosclerosis in wild type animals, the “Western” purified diet can be modified to increase cholesterol (1-1.25%) and add a bile salt such as sodium cholate or cholic acid.Contact us for more information, modifications, or possible control diets.
Examples of purified high fat diets with added cholesterol and cholate source*:
TD.0202821% milkfat (1.25% cholesterol, 0.5% cholic acid)
TD.0923715% milkfat diet (1% cholesterol, 0.5% sodium cholate)
Examples of purified high fat diets with added cholesterol (without cholate source):
TD.9612121% milkfat (1.25% cholesterol)
Research Use:
Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) primarily in wild type mice and rats.
Will not promote obesity.
Key dietary features:
High fat diet (15-20% by weight; 34 – 45% kcal from fat)
Saturated fatty acids (SFA >55% of total fatty acids)
Milkfat/butterfat, cocoa butter
Sucrose (30-50% by weight)
Cholesterol (1 – 1.25%)
Cholate source (0.5%)*
References:
1.Bernal, C., et al., Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis.J Nutr Biochem, 2013.24(11): p.1870-81.
2.Gao, Q., et al., Atherogenic diets exacerbate colitis in mice deficient in glutathione peroxidase.Inflamm Bowel Dis, 2010.16(12): p.2043-54.
3.Lichtman, A.H., et al., Hyperlipidemia and atherosclerotic lesion development in LDL receptor-deficient mice fed defined semipurified diets with and without cholate.Arterioscler Thromb Vasc Biol, 1999.19(8): p.1938-44.
4.Marcondes, M.C., et al., Effects of chronic mental stress and atherogenic diet on the immune inflammatory environment in mouse aorta.Brain Behav Immun, 2011.25(8): p.1649-57.
5.Nishina, P.M., et al., Effects of dietary fats from animal and plant sources on diet-induced fatty streak lesions in C57BL/6J mice.J Lipid Res, 1993.34(8): p.1413-22.
6.Nishina, P.M., et al., Atherosclerosis and plasma and liver lipids in nine inbred strains of mice.Lipids, 1993.28(7): p.599-605.
7.Yue, P., et al., Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice.PLoS One, 2010.5(3): p.e9906.
8.Nishina, P.M., J. Verstuyft, and B. Paigen, Synthetic low and high fat diets for the study of atherosclerosis in the mouse.J Lipid Res, 1990.31(5): p.859-69.
*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis.However, if including a cholate source is not desired for your research, diets without cholate are available.SeeTD.96121for a purified diet andTD.94059for a hybrid diet.Contact us for additional options.
Hybrid high fat diets with added cholesterol and cholate source*
Beverly Paigen and colleagues first characterized atherosclerosis development in C57BL/6 mice by feeding a hybrid atherogenic diet.The hybrid diet was created by mixing a natural ingredient mouse diet in a 3:1 ratio with a concentrated purified diet (containing 5% cholesterol and 2% sodium cholate; referred to as Thomas-Hartroft diet).The resulting mixture recreated inTD.88051/TD.90221(same formula) contains ~15.8% fat, 1.25% cholesterol, and 0.5% sodium cholate.This group later compared the hybrid atherogenic diet approach to the more modern “western” purified atherogenic diet with added cholesterol and cholate and found that the hybrid atherogenic diet induced more gallstones and liver damage.Hybrid diets contain a variety of unrefined ingredients that may modify lipid metabolism and atherogenesis and do not allow for precise control of ingredients and nutrients for the study of chronic diseases.Although more refined diets have been developed, hybrid atherogenic diets are still popular for inducing mild atherosclerosis and gallstones in wild type mice and rats.Contact us for more information, modifications, or possible control diets.
Examples of hybrid high-fat diets with added cholesterol and cholate source*:
TD.88051andTD.90221(same formula) are Teklad product codes for hybrid atherogenic diets
Example of hybrid high-fat diet with added cholesterol (without cholate source):
TD.94059
Research Use:
Induce hypercholesterolemia and mild atherosclerosis (foam cells, fatty streaks) primarily in wild type mice and rats.
Will not promote obesity.
Also used for lithogenic (gallstone) rodent studies.
Key dietary features:
75% rodent breeder diet; 25% purified ingredients
High fat (~15% by weight; 37% kcal from fat)
Saturated fatty acids (SFA >45% of total fatty acids)
Cholesterol (1.25%)
Cholate source (0.5%)*
References:
1.Nishina, P.M., J. Verstuyft, and B. Paigen, Synthetic low and high fat diets for the study of atherosclerosis in the mouse.J Lipid Res, 1990.31(5): p.859-69.
2.Clee, S.M., et al., Plasma and vessel wall lipoprotein lipase have different roles in atherosclerosis.J Lipid Res, 2000.41(4): p.521-31.
3.George, J., et al., Enhanced fatty streak formation in C57BL/6J mice by immunization with heat shock protein-65.Arterioscler Thromb Vasc Biol, 1999.19(3): p.505-10.
4.Miyake, J.H., et al., Transgenic expression of cholesterol-7-alpha-hydroxylase prevents atherosclerosis in C57BL/6J mice.Arterioscler Thromb Vasc Biol, 2002.22(1): p.121-6.
5.Paigen, B., et al., Quantitative assessment of atherosclerotic lesions in mice.Atherosclerosis, 1987.68(3): p.231-40.
6.Schreyer, S.A., D.L. Wilson, and R.C. LeBoeuf, C57BL/6 mice fed high fat diets as models for diabetes-accelerated atherosclerosis.Atherosclerosis, 1998.136(1): p.17-24.
7.Vergnes, L., et al., Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression.J Biol Chem, 2003.278(44): p.42774-84.
*Sodium cholate or cholic acid aid cholesterol and fat absorption and reduce cholesterol disposal via bile acid synthesis.However, if including a cholate source is not desired for your research, diets without cholate are available.SeeTD.96121for a purified diet andTD.94059for a hybrid diet.Contact us for additional options.
Standard diets with added cholesterol
Standard, natural ingredient diets with cholesterol added are fed to induce hypercholesterolemia.Various levels of cholesterol, fat, and/or bile salts can be added to one of the numerous standard rodent diets stocked by Envigo Teklad.For many applications, adding these components to Envigo’s minimal-to-moderate phytoestrogen global rodent diets is recommended.Our minimal phytoestrogen global rodent diets are soybean meal free, limiting the effect of phytoestrogens on your research outcomes.Soybean meal, a common dietary source of phytoestrogens, has been shown to decrease aortic fatty streak development and modify plasma cholesterol, which may reduce the risk of developing atherosclerosis.Limiting dietary soybean meal may reduce confounding variables within your dietary-induced atherosclerosis model.Contact a nutritionist to discuss additional diet options.
Examples of minimal and moderate phytoestrogen rodent diets with added cholesterol:
TD.1200971% cholesterol diet (2020 – minimal phytoestrogens)
TD.078412% cholesterol diet (2016 – minimal phytoestrogens)
TD.013832% cholesterol (2018 – Moderate phytoestrogens)
Research use:
Induce hypercholesterolemia in genetically-modified and wild type models without promoting obesity.
Key dietary features:
Standard, grain-based rodent diet
Minimal/moderate phytoestrogen diets recommended
Cholesterol (1 – 4%)
References:
1.Belch, J.J., et al., Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo.Microvasc Res, 2013.85: p.86-92.
2.Hartvigsen, K., et al., A diet-induced hypercholesterolemic murine model to study atherogenesis without obesity and metabolic syndrome.Arterioscler Thromb Vasc Biol, 2007.27(4): p.878-85.
Diets for additional animal models of atherosclerosis
Rabbits, hamsters, and swine are common models of atherosclerosis.Contact a nutritionist for information and formula examples.Seerabbit, swine and other speciesfor information and formula examples.
“西方”纯正致动脉粥样硬化饮食

“西式”饮食被喂给基因修饰的心血管模型,如APOE和Ldlr缺乏的小鼠,以加速和促进高胆固醇血症和斑块形成,并引出通常与代谢综合征相关的表型。在动脉粥样硬化的文献中,“西方”饮食通常被描述为含有20-23%乳脂/蝴蝶脂肪、0.2%总胆固醇和34%蔗糖的纯啮齿动物饮食。TD.88137这是一种“西式”饮食的例子,最初的目的是在一种新生成的APOE缺陷小鼠模型中描述和促进动脉粥样硬化的发展。联系我们,以获得更多关于“西方”风格的饮食,修改,或可能的控制饮食。
例子:

  • TD.88137调整卡路里饮食(42%来自脂肪,0.2%总胆固醇)
  • TD.1088545%脂肪KCAL饮食(总胆固醇0.2%)

研究用途:
加速高胆固醇血症和斑块形成的转基因模型,如APOE和Ldlr缺乏的小鼠。
用于饮食诱导肥胖的各种啮齿动物模型。
主要饮食特征:

  • 高脂肪饮食(按体重计算占20-23%;脂肪占40-45%)
  • 饱和脂肪酸(SFA>总脂肪酸的60%)
  • 乳脂/乳脂
  • 蔗糖(按重量计占34%)
  • 胆固醇(总数0.2%)
野生型小鼠和大鼠一般对动脉粥样硬化有抵抗力,需要更极端的饮食操作来改变脂蛋白谱,形成轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。现代配方完全是由纯化成分制成的,因为据报道,这种更精细的方法可以减少较少精制和较传统饮食方法引起的胆结石和肝脏损害的发生率。为了在野生型动物中诱导轻度动脉粥样硬化,可对“西方”纯化饲料进行改良,以提高胆固醇(1-1.25%),并添加胆酸钠或胆酸等胆盐。联系我们获得更多的信息,修改,或可能的控制饮食。
添加胆固醇和胆酸盐来源的纯化高脂饮食的例子*:

  • TD.0202821%乳脂(1.25%胆固醇,0.5%胆酸)
  • TD.0923715%乳脂饮食(1%胆固醇,0.5%胆酸钠)

添加胆固醇的纯化高脂饮食的例子(没有胆酸来源):

  • TD.9612121%乳脂(1.25%胆固醇)

研究用途:
主要在野生型小鼠和大鼠诱发高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。
不会助长肥胖。
主要饮食特征:

  • 高脂饮食(体重15-20%;脂肪34-45千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的55%)
  • 乳脂/黄油、可可脂
  • 蔗糖(重量占30%-50%)
  • 胆固醇(1-1.25%)
  • 巧克力源(0.5%)*

*胆酸钠或胆酸有助胆固醇和脂肪的吸收,并可透过胆汁酸合成减少胆固醇的排出。然而,如果你的研究不想包括胆酸盐的来源,没有胆酸盐的饮食是可用的。看见TD.96121为了纯正的饮食TD.94059混合饮食。请与我们联系,了解其他选项。

贝弗利·派根和他的同事首先通过喂养一种混合性动脉粥样硬化饮食来描述C57BL/6小鼠动脉粥样硬化的发展。这种混合饲料是通过将一种天然成分的老鼠饲料按3:1的比例与浓缩的纯化饲料(含5%胆固醇和2%胆酸钠;称为Thoms-Hartroft饮食)混合而成的。产生的混合物在TD.88051/TD.90221(同配方)含有~15.8%脂肪、1.25%胆固醇和0.5%胆酸钠。这组人后来将混合动脉粥样硬化饮食方法与更现代的“西方”纯化动脉粥样硬化饮食方法进行了比较,并添加了胆固醇和胆酸盐,发现混合动脉粥样硬化饮食会导致更多的胆结石和肝脏损伤。混合饮食含有多种未精制的成分,这些成分可能会改变血脂代谢和动脉粥样硬化的发生,并且不允许对成分和营养物进行精确控制,以用于慢性病的研究。虽然已经开发出了更精细的饮食,但混合动脉粥样硬化饮食仍然是野生型小鼠和大鼠诱发轻度动脉粥样硬化和胆结石的流行食品。联系我们获得更多的信息,修改,或可能的控制饮食。
添加胆固醇和胆酸盐的混合高脂饮食实例*:

  • TD.88051和TD.90221(相同的配方)是特克拉德混合动脉粥样硬化饮食的产品代码。

添加胆固醇的混合高脂饮食的例子(没有胆酸来源):

  • TD.94059

研究用途:
主要在野生型小鼠和大鼠诱发高胆固醇血症和轻度动脉粥样硬化(泡沫细胞、脂肪条纹)。
不会助长肥胖。
也用于造石(胆石)啮齿动物的研究。
主要饮食特征:

  • 75%的啮齿动物饲养员;25%的纯化成分
  • 高脂肪(体重约15%;脂肪37%千卡)
  • 饱和脂肪酸(SFA>总脂肪酸的45%)
  • 胆固醇(1.25%)
  • 巧克力源(0.5%)*

*胆酸钠或胆酸有助胆固醇和脂肪的吸收,并可透过胆汁酸合成减少胆固醇的排出。然而,如果你的研究不想包括胆酸盐的来源,没有胆酸盐的饮食是可用的。看见TD.96121为了纯正的饮食TD.94059混合饮食。请与我们联系,了解其他选项。

标准的,添加胆固醇的天然成分饮食是用来诱导高胆固醇血症的。不同水平的胆固醇,脂肪和/或胆汁酸盐可以添加到众多的标准啮齿动物饮食之一,由EnvigoTeclad。在许多应用中,建议将这些成分添加到Envigo的最小到中等植物雌激素的全球啮齿动物饮食中。我们最小的植物雌激素全球啮齿动物饮食是不含豆粕的,限制了植物雌激素对你的研究结果的影响。豆粕是一种常见的植物雌激素来源,它可以减少主动脉脂肪条纹的发育,改善血浆胆固醇,从而降低动脉粥样硬化的风险。限制饮食豆粕可能会减少饮食诱导动脉粥样硬化模型中的混杂变量。联系营养学家讨论其他饮食选择。
添加胆固醇的最小和中度植物雌激素啮齿动物饮食的例子:

  • TD.120097  1%胆固醇饮食(2020年-最小植物雌激素)
  • TD.07841  2%胆固醇饮食(2016年-最小植物雌激素)
  • TD.01383  2%胆固醇(2018年-中度植物雌激素)

研究用途:
在转基因和野生型模型中诱导高胆固醇血症而不促进肥胖。
主要饮食特征:

  • 标准的、以谷物为基础的啮齿动物饮食
  • 最小/中度植物雌激素饮食建议
  • 胆固醇(1-4%)
兔子、仓鼠和猪是动脉粥样硬化的常见模型。请与营养师联系,了解有关信息和公式示例。看见兔子、猪和其他物种有关信息和公式示例。

Harlan蛋白质调节饲料 Protein adjusted diets

Harlan蛋白质调节饲料 Protein adjusted diets
Teklad diet, bedding and enrichment + Teklad laboratory animal diets + Custom research diets + Protein adjusted diets
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Harlan蛋白质调节饲料 Protein adjusted diets
Protein adjusted diets | Envigo
A few protein adjusted formulas are shown below. Please contact us for additional formulas of this nature or for more information about altering the protein type or content of a diet.
Formula examples:
TD.93328      “Protein free” diet
TD.90016      6% Protein diet
TD.91352       20% Protein diet
TD.90018      40% Protein diet
These diet examples are from a series of diets with the following features: casein-based, isocaloric (3.8 kcal/g) and matched for fat (5.5%), calcium (0.7%), and phosphorus (0.54%).  There are other diets available from this series of diets, as well as other unique protein adjusted diets.
Casein is the most widely used refined protein source, but it is also possible to use other refined protein sources, such as “vitamin-free” test casein (alcohol extracted), lactalbumin, isolated soy protein, and egg white solids. These particular protein sources are usually used to achieve a specific research objective, rather than for routine use. For instance, vitamin-free test casein is most appropriately used in vitamin deficient diets, and egg white solids is most suitable for zinc or biotin deficient diets.
Adjusted protein diets usually range from “protein-free” (trace) to 60% protein, depending on the research.
一些蛋白质调整的公式如下所示。请与我们联系,以获得更多的这种性质的配方,或更多有关改变蛋白质类型或饮食内容的信息。
公式示例:
TD.93328“无蛋白质”饮食
TD.90016  6%蛋白质饮食
TD.91352  20%蛋白质饮食
TD.90018  40%蛋白质饮食
这些饮食的例子来自一系列的饮食,有以下特点:酪蛋白为基础,等热量(3.8千卡/克),与脂肪(5.5%),钙(0.7%)和磷(0.54%)匹配。从这一系列的饮食中可以得到其他的饮食,以及其他独特的蛋白质调整的饮食。
酪蛋白是最广泛使用的精制蛋白质来源,但也可以使用其他精制蛋白质来源,如“无维生素”测试酪蛋白(醇提),乳清蛋白,分离大豆蛋白和蛋清固体。这些特定的蛋白质来源通常用于实现特定的研究目标,而不是用于常规用途。例如,无维生素测试酪蛋白最适合用于缺乏维生素的饮食,而蛋清固体最适合于锌或生物素缺乏的饮食。
根据研究结果,调整后的蛋白质饮食通常从“无蛋白质”(微量)到60%的蛋白质。
上海金畔生物科技有限公司(www.jinpanbio.com)提供生命科学研究领域系列产品,包括生化试剂、诊断试剂、色谱标准品和实验仪器耗材。主营Lumiprobe Cy系列活性荧光染料;修饰性PEG(Laysan bio、NANOCS、Avanti等进口品牌PEG以及定制合成修饰性聚乙二醇、单分散小分量PEG);Sigma、Amresco、TCI、MP bio生化试剂;WAKO日本和光纯药、日本关东化学Kanto试剂、日本三菱、日本柴田科学SIBATA;Megazyme食品分析检测试剂盒、日本共立理化学;Research diets、Harlan饲料、Bio-Serv、日本CLEA Japan品牌的动物饲料;Oxoid、Nissui日水、日本荣研、BD difco、Himedia品牌微生物培养基;免疫诊断试剂包括:Bethyl抗体;Biolegend流式抗体、Abcam、CST、Santa Cruz抗体;Roche、TOYOBO、NEB品牌的酶;中检所、TRC、药典USP、EP、Reagecon标准品;耗材和仪器包括Whatman、日本Advantec滤膜、Millipore品牌的各种滤膜、滤器和柱子填料等、Hampton蛋白结晶试剂耗材、老鼠软管灌胃针、动物毛发记号笔、Labnet、Wheaton瓶子、Bio-Rad伯乐、康宁Corning、Axygen、Falcon 、Eppendorf、Nunc、Nalgene、Nest品牌的培养皿、培养板、离心机、离心管、移液枪及枪头等实验室常用仪器耗材。
上海金畔生物科技有限公司
服务热线:18301939375   QQ:3258089810    3259632176
Email:  info@jinpanbio.com
官网:http://www.jinpanbio.com

Harlan矿物质调节饲料Mineral adjusted diets

Harlan矿物质调节饲料Mineral adjusted diets
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Mineral adjusted diets
A few mineral adjusted formulas are shown below. Please contact us for additional formulas of this nature or for more information about altering the mineral profile of a diet. Read below for more information.
Formula examples:
TD.80396      Iron deficient diet
TD.85419      Zinc deficient diet
TD.88239      Potassium deficient diet
TD.95027      Low calcium diet (0.4% P)
TD.96348      Diet (20% lactose, 2% Ca, 1.25% P)
TD.92163      Selenium deficient diet
TD.95125      Iodine deficient (0.15% PTU)
Unique protein ingredients may be necessary to minimize background levels of certain minerals. Other steps taken to minimize background mineral contamination include the use of reagent grade minerals when necessary or omission of certain ingredients. Specialized mineral premixes may be used in these diets, or minerals are added individually to the diet in order to control the level of specific minerals.
With the exception of sodium, it is necessary to use refined ingredients to achieve the lowest possible levels of minerals in a diet.
From this mineral deficient base, various levels of minerals can be added back. Some formulas adjust multiple minerals, and other related nutrients.
Contact us to discuss other possibilities for the minerals listed above, and for those minerals not listed here.
一些矿物调整公式如下所示。请与我们联系,以获得更多的这种性质的配方,或更多的信息,改变矿物质的饮食。有关更多信息,请阅读下面。
公式示例:
TD.80396缺铁饮食
TD.85419缺锌饮食
TD.88239缺钾饮食
TD.95027低钙饮食(0.4%P)
TD.96348日粮(20%乳糖,2%钙,1.25%P)
TD.92163缺硒饮食
TD.95125缺碘(0.15%PTU)
独特的蛋白质成分可能是必要的,以尽量减少某些矿物质的背景水平。为尽量减少背景矿物污染而采取的其他步骤包括在必要时使用试剂级矿物或遗漏某些成分。在这些饮食中可以使用特殊的矿物预混料,也可以在饮食中单独添加矿物质,以控制特定矿物质的含量。
除钠外,必须使用精制成分,以达到饮食中矿物质含量尽可能低的水平。
从这种矿物缺乏的基础,不同水平的矿物可以补充回来。一些配方调整多种矿物质和其他相关营养素。
上海金畔生物科技有限公司(www.jinpanbio.com)提供生命科学研究领域系列产品,包括生化试剂、诊断试剂、色谱标准品和实验仪器耗材。主营Lumiprobe Cy系列活性荧光染料;修饰性PEG(Laysan bio、NANOCS、Avanti等进口品牌PEG以及定制合成修饰性聚乙二醇、单分散小分量PEG);Sigma、Amresco、TCI、MP bio生化试剂;WAKO日本和光纯药、日本关东化学Kanto试剂、日本三菱、日本柴田科学SIBATA;Megazyme食品分析检测试剂盒、日本共立理化学;Research diets、Harlan饲料、Bio-Serv、日本CLEA Japan品牌的动物饲料;Oxoid、Nissui日水、日本荣研、BD difco、Himedia品牌微生物培养基;免疫诊断试剂包括:Bethyl抗体;Biolegend流式抗体、Abcam、CST、Santa Cruz抗体;Roche、TOYOBO、NEB品牌的酶;中检所、TRC、药典USP、EP、Reagecon标准品;耗材和仪器包括Whatman、日本Advantec滤膜、Millipore品牌的各种滤膜、滤器和柱子填料等、Hampton蛋白结晶试剂耗材、老鼠软管灌胃针、动物毛发记号笔、Labnet、Wheaton瓶子、Bio-Rad伯乐、康宁Corning、Axygen、Falcon 、Eppendorf、Nunc、Nalgene、Nest品牌的培养皿、培养板、离心机、离心管、移液枪及枪头等实验室常用仪器耗材。
上海金畔生物科技有限公司
服务热线:18301939375   QQ:3258089810    3259632176
Email:  info@jinpanbio.com
官网:http://www.jinpanbio.com

Harlan teklad 碳水化合物调节饲料Carbohydrate adjusted

Harlan teklad 碳水化合物调节饲料Carbohydrate adjusted
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Harlan teklad 碳水化合物调节饲料Carbohydrate adjusted
Carbohydrate adjusted
A few carbohydrate adjusted formulas are shown below. Please contact us for additional formulas of this nature or for more information about altering the carbohydrate profile of a diet.
Formula examples:
TD.89247      60% Fructose diet
TD.86489      Diet with adjusted sucrose/cornstarch
TD.96348      Diet (20% lactose, 2% Ca, 1.25% P)
TD.98090      70% Carbohydrate diet
TD.96355      Ketogenic diet (almost no carbohydrate)
Carbohydrates often make up the majority (by weight and % kcal) of custom research diets, with the exception of higher fat diets. Commonly used carbohydrate sources include sucrose, cornstarch and maltodextrin. Other sources include fructose, dextrose (glucose), dextrin, and lactose. Maltodextrin is enzymatically derived from cornstarch to have shorter glucose polymers and is helpful in pelleting high fat diets and in diets where cornstarch exceeds sucrose.
Sucrose is a part of most formulas, often making up 10% of the diet or more. This likely adds to the palatability of the diet. The carbohydrate profile of a diet can be manipulated, although some mixtures may not pellet. There are also diets with very little carbohydrate, thus containing high amounts of fat and/or protein.
Cellulose (fiber) is part of many formulas and while not required by rodents, is considered beneficial. It can also be used to make formulas with differing macronutrient profiles isocaloric.
一些碳水化合物调整公式如下所示。请与我们联系,以获得更多的这种性质的配方,或更多有关改变饮食的碳水化合物的信息。
公式示例:
TD.8924760%果糖饮食
TD.86489调整蔗糖/玉米淀粉的饮食
TD.96348日粮(20%乳糖,2%钙,1.25%P)
TD.9809070%碳水化合物饮食
TD.96355生酮饮食(几乎没有碳水化合物)
碳水化合物往往占大多数(按体重和%千卡)的习惯研究饮食,除了高脂肪饮食。常用的碳水化合物来源包括蔗糖、玉米淀粉和麦芽糊精。其他来源包括果糖、葡萄糖、糊精和乳糖。麦芽糊精是从玉米淀粉中得到的酶解物,它含有较短的葡萄糖聚合物,有助于高脂饲料的颗粒化和玉米淀粉超过蔗糖的饮食。
蔗糖是大多数配方的一部分,通常占饮食的10%或更多。这可能会增加饮食的适口性。饮食中的碳水化合物可以被操纵,尽管有些混合物可能不是颗粒。也有很少碳水化合物的饮食,因此含有大量的脂肪和/或蛋白质。
纤维素(纤维)是许多配方的一部分,虽然不是啮齿动物所必需的,但被认为是有益的。它也可以用来制作不同的黄金分割配方等热量。
上海金畔生物科技有限公司(www.jinpanbio.com)提供生命科学研究领域系列产品,包括生化试剂、诊断试剂、色谱标准品和实验仪器耗材。主营Lumiprobe Cy系列活性荧光染料;修饰性PEG(Laysan bio、NANOCS、Avanti等进口品牌PEG以及定制合成修饰性聚乙二醇、单分散小分量PEG);Sigma、Amresco、TCI、MP bio生化试剂;WAKO日本和光纯药、日本关东化学Kanto试剂、日本三菱、日本柴田科学SIBATA;Megazyme食品分析检测试剂盒、日本共立理化学;Research diets、Harlan饲料、Bio-Serv、日本CLEA Japan品牌的动物饲料;Oxoid、Nissui日水、日本荣研、BD difco、Himedia品牌微生物培养基;免疫诊断试剂包括:Bethyl抗体;Biolegend流式抗体、Abcam、CST、Santa Cruz抗体;Roche、TOYOBO、NEB品牌的酶;中检所、TRC、药典USP、EP、Reagecon标准品;耗材和仪器包括Whatman、日本Advantec滤膜、Millipore品牌的各种滤膜、滤器和柱子填料等、Hampton蛋白结晶试剂耗材、老鼠软管灌胃针、动物毛发记号笔、Labnet、Wheaton瓶子、Bio-Rad伯乐、康宁Corning、Axygen、Falcon 、Eppendorf、Nunc、Nalgene、Nest品牌的培养皿、培养板、离心机、离心管、移液枪及枪头等实验室常用仪器耗材。
上海金畔生物科技有限公司
服务热线:18301939375   QQ:3258089810    3259632176
Email:  info@jinpanbio.com
官网:http://www.jinpanbio.com

Harlan teklad品牌饲料分类

Harlan teklad品牌饲料分类
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Teklad diet, bedding and enrichment + Teklad laboratory animal diets + Custom research diets
Custom diets are developed for a specific purpose and benefit from your input and our expertise
Determining the most appropriate diet for your research model can be challenging, but we are here to help. With more than 20,000 unique formulas in our database attained over 40 years, Envigo nutritionists have vast experience to draw upon. To meet the progressive demands of science and to serve you better, we continually add to our database as we acquire new knowledge.
Common uses for custom diets include:
Control Nutrients
Vitamin or mineral adjusted
Protein or amino acid adjusted
Lipid or fatty acid adjusted
Induce Disease
Atherogenic (cholesterol, fat, cholate)
Diet-induced obesity (40-60% kcal from fat)
High carbohydrate (fructose, sucrose)
NaCl adjusted
Cuprizone demyelination
Dose Animals
Control gene expression – doxycycline or tamoxifen containing diets
Addition of customer-supplied ingredients/compounds
You can select from the wide variety of existing diets, or one designed specifically for your purposes. Either way, we encourage you to contact us for complimentary consultation with our nutritionists.
A small number of representative custom research diet formulas are found on our website. If you are unable to find a product code or formula description cited in a publication, or one used previously by your lab or others, contact us.
定制饮食是为了特定的目的而制定的,并得益于您的投入和我们的专业知识。
为你的研究模式确定最合适的饮食是很有挑战性的,但我们是来帮忙的。在我们的数据库中,已有超过20,000种独特的配方,40多年来,Envigo营养学家有着丰富的经验可供借鉴。为了满足科学进步的需求,并更好地为您服务,我们不断地在我们的数据库中添加新的知识。
习惯饮食的常见用途包括:
控制养分
维生素或矿物调整后
蛋白或氨基酸调整后
脂或脂肪酸调整后
诱发病
动脉粥样硬化(胆固醇、脂肪、胆酸盐)
饮食型肥胖(脂肪40%-60千卡)
高碳水化合物(果糖,蔗糖)
NaCl调节
铜带脱髓鞘
剂量动物
控制基因表达-强力霉素或他莫昔芬含粮
加法客户供应的配料/化合物
你可以从各种各样的现有饮食中选择,或者是专门为你的目的而设计的。无论哪种方式,我们都鼓励您与我们的营养学家进行免费咨询。
Harlan teklad品牌饲料分类

实验动物饲料 Teklad laboratory animal diets
标准天然成分饮食 Standard natural ingredient diets
定制研究饮食 Custom research diets
AIN饮食配方 AIN diet formulas
动脉粥样硬化 Atherogenic
饮食诱导肥胖 Diet induced obesity
脂肪/脂调节 Fat/lipid adjusted
碳水化合物调节 Carbohydrate adjusted
蛋白质调节饮食 Protein adjusted diets
维生素调整饮食 Vitamin adjusted diets
矿物调节饮食 Mineral adjusted diets
盐调节(天然成分) NaCl adjusted (natural ingredient)
氨基酸定义 Amino acid defined
多西环素饮食 Doxycycline diets
他莫昔芬饮食 Tamoxifen diets
客户供应的配料 Customer supplied ingredients
基混合体 Basal mixes
异黄酮调节 Isoflavone adjusted
兔子、猪和其他物种 Rabbit, swine and other species
饮食成分 Diet ingredients
药物饮食 Medicated diets

Harlan MCD饲料 TD.90262 Methionine/Choline Deficient Diet

Harlan MCD饲料 TD.90262 Methionine/Choline Deficient Diet
品牌:Harlan Teklad
货号:TD.90262
英文名称:Methionine/Choline Deficient Diet
别名:MCD饲料
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。

Amino acid defined | Envigo

A few amino acid defined formulas are shown below. This type of diet is used when a diet needs to be deficient in one or more amino acids, or adjustments need to be made to specific amino acid levels.
Formula examples:

  • TD.99366      Amino acid diet
  • TD.90262      Methionine and choline deficient diet
  • TD.00434      Folic acid deficient diet
  • TD.99386      No lysine AA diet

Sometimes this type of diet is used to further reduce the background level of certain vitamins that are found in protein sources such as casein or vitamin-free (alcohol extracted) casein. Some folic acid deficient diets utilize this approach.
The amino acid profile for most amino acid defined diets is based on work by Harper and Rogers (J. Nutr. (1965) 87:267-276) and is not representative of the amino acid profile of an intact protein source such as casein. Other amino acid profiles can be specified. When an amino acid(s) is removed or reduced, isonitrogenous adjustment can be made if required.

Harlan MCD饲料 TD.90262 Methionine/Choline Deficient Diet
 

Harlan TD.09682 高酯饲料 42% Fat Calories Diet (Western, Blue)说明书

Harlan TD.09682 高酯饲料 42% Fat Calories Diet (Western, Blue)说明书
货号:TD.09682
品牌:Harlan
英文名称:42% Fat Calories Diet (Western, Blue)
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Harlan TD.09682 高酯饲料 42% Fat Calories Diet (Western, Blue)说明书
Formula                            g/Kg
Casein                                195.0
DL-Methionine                       3.0
Sucrose                              341.46
Corn Starch                          150.0
Anhydrous Milkfat                      210.0
Cholesterol                            1.5
Cellulose                              49.85
Mineral Mix, AIN-76 (170915)            35.0
Calcium Carbonate                     4.0 +
Vitamin Mix, Teklad (40060)              10.0
Ethoxyquin,                            0.04
Blue Food Color                        0.15
Key Features
+ Purified Diet
+ Atherogenic
+ Modification of TD.88137
+ Color Coded
Key Planning Information
+ Products are made fresh to order
+Store product at 4°C or lower
+Use within 6 months (applicable to most diets)
+ Box labeled with product name, manufacturing date, and lot number
+ Replace diet at minimum once per week  More frequent replacement may be advised
+ Lead time:

  • 2 weeks non-irradiated
  • 4 weeks irradiated

Footnote
Modification of TD.88137 to add blue coloring.
Product Specific Information
+ 1/2″ Pellet or Powder (crumbly)
+ Minimum order 3 Kg
+ Irradiation available upon request
+ Vacuum packaging (1 and 2 Kg)

Harlan肥胖模型高酯饲料 Diet induced obesity

Harlan肥胖模型高酯饲料 Diet induced obesity
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Harlan肥胖高酯模型
Diet induced obesity
 
Purified high fat diets used to induce obesity and obesity-related complications such as diabetes and metabolic syndrome typically have 40-60% of energy derived from fat. The diet tables below summarize relevant diet features for several Teklad custom research diets commonly used in rodent models.
Teklad also creates high-fat diets for other species, including pigs, primates, and dogs. Contact us to discuss the use of these diets or one that better meets your needs.

Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 55-60% of calories from fat
       
Diet features TD.06414 stocked TD.93075 dough TD.07011 pellet
Kcal/g 5.1 4.8
Fat, % Kcal 60 55
Fat Sources,
% by weight
31% lard
3% soybean oil
27.4% vegetable shortening
1.6% corn oil
Fatty acid profile,
% total fat
37% saturated
47% monounsaturated
16% polyunsaturated
28% saturated, 30% trans
28% monounsaturated (cis)
14% polyunsaturated (cis)
Sucrose,
% by weight
12.1 9.6
Notes 60F10S poster data
Compare to D12492
Trans fat
Example modifications TD.08500 coconut oil
TD.09766 milk fat
 
Ingredient matched,
low fat control diets*
TD.06416 (35% sucrose)
TD.08806 (11% sucrose)
TD.93074 (21% sucrose)
TD.120651 (7% sucrose)
References Mouse
Rat
Mouse
Rat

*Control diets can be designed in several ways, depending on what features the researcher wants to modify relative to the high-fat diet. These are just a few examples.

 
Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 40-45% of calories from fat
         
Diet features TD.06415 TD.08811 TD.88137 stocked TD.95217
Kcal/g 4.6 4.7 4.5 4.3
Fat, % Kcal 45 45 42 40
Fat sources,
% by weight
19.5% lard
3% soybean oil
21% milk fat
2% soybean oil
21% milk fat 10.6% vegetable shortening
4% milk fat
4% soybean oil
Fatty acid profile,
% total fat
36% saturated
46% monounsaturated
18% polyunsaturated
61% saturated
31% monounsaturated
8% polyunsaturated
62% saturated
27% monounsaturated
5% polyunsaturated
34% saturated, 18% trans
29% monounsaturated (cis)
19% polyunsaturated (cis)
Sucrose,
% by weight
22.8 36.8 34.5 15.8
Notes Compare to D12451 45F30S poster data “Western Diet”
Cholesterol added
Trans fat
Example modifications TD.110716 milk fat
TD.10670 no dye
TD.130784 lard
TD.120438 no dye
TD.07201 lard
TD.00573 h-coconut oil, no cholesterol
TD.09682 blue dye
TD.07734 green dye
Ingredient matched,
low fat control diets*
TD.06416 (35% sucrose)
TD.110675 (18% sucrose)
TD.120455 (6% sucrose, resistant starch)
TD.120724 (14% sucrose)
TD.05230 (34% sucrose)
TD.08485 (12% sucrose)
TD.06101 (6% sucrose)
References Mouse
Rat
Mouse
Rat
Mouse
Rat
Mouse
Rat

饮食诱导肥胖

用于诱导肥胖和肥胖相关并发症(如糖尿病和代谢综合征)的纯化高脂饮食通常有40-60%的能量来源于脂肪。下面的饮食表总结了一些特克拉德定制研究饮食的相关饮食特征,这些研究饮食通常用于啮齿类动物模型。
泰克乐还为其他物种,包括猪、灵长类动物和狗创造高脂肪饮食。联系我们讨论使用这些饮食或更好地满足您的需要。

通常使用的饮食诱导肥胖(DIO)技术啮齿动物饮食中含有55-60%的热量来自脂肪。
       
饮食特征 TD.06414 备好 TD.93075 面团 TD.07011 球团
千卡/克 5.1 4.8
脂肪,%千卡 60 55
脂肪来源,
按重量计百分比
31%猪油
3%豆油
27.4%蔬菜酥油
1.6%玉米油
脂肪酸谱,
总脂肪百分比
37%饱和
47%单不饱和
16%多不饱和
28%饱和,30%反式
28%单不饱和(顺式)
14%多不饱和
蔗糖
按重量计百分比
12.1 9.6
注记 60F10S海报数据
与D 12492比较
反式脂肪
示例修改 TD.08500椰子油
TD.09766乳脂
 
成分匹配,
低脂控制饮食*
TD.06416(35%蔗糖)
TD.08806(11%蔗糖)
TD.93074(21%蔗糖)
TD.120651(7%蔗糖)
参考文献
大鼠

大鼠

*控制饮食可以通过几种方式来设计,这取决于研究人员相对于高脂肪饮食想要改变什么特征。这些只是几个例子。

 
通常使用的饮食诱导肥胖(DIO)技术啮齿动物饮食中含有40-45%的热量来自脂肪。
         
饮食特征 TD.06415 TD.08811 TD.88137 备好 TD.95217
千卡/克 4.6 4.7 4.5 4.3
脂肪,%千卡 45 45 42 40
脂肪来源,
按重量计百分比
19.5%猪油
3%豆油
21%乳脂
2%豆油
21%乳脂 10.6%蔬菜酥油
4%乳脂
4%豆油
脂肪酸谱,
总脂肪百分比
36%饱和
46%单不饱和
18%多不饱和
61%饱和
31%单不饱和
8%多不饱和
62%饱和
27%单不饱和
5%多不饱和
34%饱和,18%反式
29%单不饱和(顺式)
19%多不饱和
蔗糖
按重量计百分比
22.8 36.8 34.5 15.8
注记 与D 12451比较 45F30S海报数据 “西餐”
添加胆固醇
反式脂肪
示例修改 TD.110716乳脂
TD.10670无染料
TD.130784猪油
TD.120438无染料
TD.07201猪油
TD.00573椰子油,不含胆固醇
TD.09682蓝色染料
TD.07734绿色染料
成分匹配,
低脂控制饮食*
TD.06416(35%蔗糖)
TD.110675(18%蔗糖)
TD.120455(6%蔗糖,抗性淀粉)
TD.120724(14%蔗糖)
TD.05230(34%蔗糖)
TD.08485(12%蔗糖)
TD.06101(6%蔗糖)
参考文献
大鼠

大鼠

大鼠

大鼠

Diets for diet-induced obesity (DIO)
Diets with 55-60% of calories from fat like TD.06414 and TD.93075 are commonly used for inducing obesity in rodents. While considered extreme compared to typical human fat consumption, these diets are effective in initiating rapid weight gain in most rodents. With higher fat content there is less room for carbohydrate, thus the carbohydrate (particularly sucrose) amount is relatively low compared to other obesity inducing diets. If you are interested in high fat and high carbohydrate, look at diets with 40-45% of calories from fat (often referred to as western diets).
As the fat level increases, pellet quality (durability) is often compromised. Some higher fat formulas are available only in non-pelleted form or require specific carbohydrate, maltodextrin, for pelleting. Depending on the fat and carbohydrate sources used, the non-pelleted form could be dense and crumbly, dough-like, or paste-like. Though a little more challenging to work with, non-pelleted diet is still used by many researchers for diet-induced obesity models as these researchers suspect the softer form may enhance obesity development.
Diets with 40-45% of calories from fat, like TD.95217, TD.88137, TD.06415, and TD.08811, represent another popular diet pattern for diet-induced obesity work. These diets have double or triple the amount of sucrose found in higher fat diets. High levels of simple carbohydrate like sucrose and fructose may help to promote hypertriglyceridemia, insulin resistance, and fatty liver. Diets with a pattern of high sucrose and high saturated or trans fat are often referred to as “Western Diets” in obesity and cardiovascular fields. Some “Western Diets” have further modifications to the fatty acid profile or even specific vitamin and minerals adjustments to be even more closely matched to a Western Diet pattern. For specific fatty acid modifications, see examples on our fat/lipid adjusted diets page.
Diets for diet-induced diabetes
Many of the same diets used for inducing obesity in rodents can be used to enhance diabetes related phenotypes like insulin resistance and glucose intolerance. However, fasting hyperglycemia characteristic of diabetes (glucose > 200 mg/dL) is uncommon with a diet only approach. Pre-feeding a high fat diet to induce a certain level of obesity and insulin resistance and then giving low-dose streptozotocin (STZ) may be an effective approach if overt hyperglycemia is desired.
Ingredient matched, low-fat DIO control diets
There are many options with different levels and types of fat in addition to different types of carbohydrate ranging from sucrose (highly refined, simple digestion) to corn starch (refined, but more complex) to resistant starch (refined, but not fully digestible). A very basic purified control diet would be AIN-93M (TD.94048) or AIN-93G (TD.94045). AIN-93 diets have a moderate amount of sucrose at ~10%, and fat is from soybean oil with a healthy fatty acid profile. Additional examples of controls for specific DIO diets can be found in the above tables.
Many researchers choose to compare their high fat fed animals to animals fed a natural ingredient, grain-based diet (also referred to as standard diets or chow). These diets differ in the source and level of nutrients as well as in the presence of non-nutritive factors (such as phytates or phytoestrogens). Depending on what your main comparisons are, it may be suitable to have a grain-based diet as your control/reference group. However, making such comparisons limits inferences to dietary patterns versus a specific dietary component.

Harlan TD.88137 高脂饲料 Adjusted Kcal Diet (42% from fat)

Harlan TD.88137 高脂饲料 Adjusted Kcal Diet (42% from fat)
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Harlan TD.88137 高脂饲料 Adjusted Kcal Diet (42% from fat)
A staple of atherosclerosis research
More than 25 years ago, our nutritionists collaborated with researchers at Rockefeller University to develop a diet with features of a ‘Western Diet’ to characterize and enhance atherosclerosis development in their newly generated Apoe deficient mouse model. With over 200 unique users worldwide, TD.88137 continues to be fed to genetically modified cardiovascular models to accelerate and enhance hypercholesterolemia and plaque formation.
Formula                                             g/Kg
Casein                                              195.0
DL-Methionine                                     3.0
Sucrose                                            341.46
Corn Starch                                       150.0
Andydrous Milkfat                               210.0
Cholesterol                                          1.5
Cellulose                                              50.0
Mineral Mix, AIN-76 (170915)               35.0
Calcium Carbonate                               4.0
Vitamin Mix, Teklad (40060)                10.0
Ethoxyquin                                          0.04
Critical dietary features of TD.88137 related to atherosclerosis development include:
++Cholesterol (0.2% total cholesterol)
++Total fat (21% by weight; 42% kcal from fat)
++High in saturated fatty acids  (>60% of total fatty acids)
++High sucrose (34% by weight)
Typical fatty acid profile of TD.88137
Typical fatty acid analysis,% of diet1                   Mean                             SD
Total                                                                    20.7                                1.5
Saturated fat                                                       12.8                                0.8
Monounsaturated fat                                             5.6                                0.5
Polyunsaturated fat                                             1.0                                  0.2
Unknown2                                                           1.3                                   0.3
Selected nutrient information1
Key points from the literature
TD.88137 has been used to accelerate atherosclerosis development in Apoe and Ldlr deficient models:
++In Apoe deficient mice, plasma cholesterol triples to >1500 mg/dL within three weeks (1, 2). Foam cell and lesion development occurs within 6-10 weeks
(2-4). Fibrous plaque formation is observed at 15 weeks with the development of fibrous caps after 20 weeks (2).
++Ldlr deficient mice fed for two weeks increase plasma cholesterol to >800 mg/dL and triglyceride to >300 mg/dL (5). After six weeks of feeding, hyperglycemia, hyperinsulinemia and dyslipidemia develop with small foam cell lesions in the aortic
arch (6, 7).
With over 420 citations, uses of TD.88137 continue to evolve and include atherosclerosis, obesity, non-alcoholic steatohepatitis (NASH), osteoporosis,
hypertension and metabolic syndrome. Contact us for a more extensive reference list.
Control diet options for TD.88137
Natural ingredient diets
++Also referred to as standard diets or chow
++Diets differ in the source and level of nutrients as well as the presence of non-nutritive factors (such as phytates or phytoestrogens) compared
to TD.88137
++Limits inferences to differences in dietary pattern versus a specific dietary component
Ingredient matched, low fat diets
++Controls for the type of ingredients, non-nutritive components and the source and level of specific nutrients
++Suggested ingredient matched, low fat dietary controls for TD.88137 listed below; data sheets can be found on our website at envigo.com
Suggested ingredient matched, low fat controls

References  参考文献
1. Plump, A.S., et al., Severe hypercholesterolemia and atherosclerosis in
apolipoprotein E-deficient mice created by homologous recombination in
ES cells. Cell, 1992. 71(2): p. 343-53.
2. Nakashima, Y., et al., Apoe-deficient mice develop lesions of all phases of
atherosclerosis throughout the arterial tree. Arterioscler Thromb, 1994.
14(1): p. 133-40.
3. Febbraio, M., et al., Targeted disruption of the class B scavenger receptor
CD36 protects against atherosclerotic lesion development in mice.
J Clin Invest, 2000. 105(8): p. 1049-56.
4. Nakashima, Y., et al., Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone
sites on the endothelium in the Apoe-deficient mouse. Arterioscler Thromb
Vasc Biol, 1998. 18(5): p. 842-51.
5. Towler, D.A., et al., Diet-induced diabetes activates an osteogenic gene regulatory
program in the aortas of low density lipoprotein receptor-deficient mice.
J Biol Chem, 1998. 273(46): p. 30427-34.
6. Tsuchiya, K., et al., FoxOs integrate pleiotropic actions of insulin in vascular
endothelium to protect mice from atherosclerosis. Cell Metab, 2012. 15(3): p. 372-81.
7. Huszar, D., et al., Increased LDL cholesterol and atherosclerosis in LDL receptordeficient
mice with attenuated expression of scavenger receptor B1. Arterioscler
Thromb Vasc Biol, 2000. 20(4): p. 1068-73.
8. Yang, B., et al., Changes of skeletal muscle adiponectin content in diet-induced
insulin resistant rats. Biochem Biophys Res Commun, 2006. 341(1): p. 209-17.
9. Schafer, K., et al., Leptin promotes vascular remodeling and neointimal growth
in mice. Arterioscler Thromb Vasc Biol, 2004. 24(1): p. 112-7.
10. Lijnen, H.R., et al., Nutritionally induced obesity is attenuated in transgenic mice
overexpressing plasminogen activator inhibitor-1. Arterioscler Thromb Vasc
Biol, 2003. 23(1): p. 78-84.
11. Maquoi, E., et al., Modulation of adipose tissue expression of murine matrix
metalloproteinases and their tissue inhibitors with obesity. Diabetes, 2002.
51(4): p. 1093-101.
12. VanSaun MN, et al. 2009. High fat diet induced hepatic steatosis establishes a
permissive microenvironment for colorectal metastases and promotes primary
dysplasia in a murine model. Am J Pathol 175:355-64.
13. Dixon LJ, et al. 2013. Caspase-1 as a central regulator of high fat diet-induced
non-alcoholic steatohepatitis. PLoS One 8:e56100.

Harlan TD.96208氯化钠调节饲料 NaCl dite

Harlan TD.96208氯化钠调节饲料 NaCl dite
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
NaCl adjusted (natural ingredient) | Harlan
The sodium content of natural ingredients such as corn, wheat, and soybean meal is low. Thus, these ingredients can be used to create a base diet that is sodium deficient. To this base diet, various amounts of sodium chloride salt (NaCl) can be added, and other ingredients adjusted slightly to maintain a relatively constant nutrient profile (with the exception of sodium and chloride). Below are examples from a popular series of adjusted NaCl diets. Contact us for more information.

Formula examples
Added NaCl (%) Approx. Na (%) no dye red* dye orange* dye blue* dye
Na deficient 0.01-0.02 TD.90228 TD.08290    
Possible control diets: 0.05% Na (0.1% NaCl) meets est. minimum Na requirement. Typical rodent diets contain 0.2%-0.4% Na (~0.5-1% NaCl).
0.1 0.05 TD.94268   TD.07334  
0.49 0.2 TD.96208   TD.110765  
1 0.4 TD.90229      
Diets for studies that look at effects of excess sodium consumption in rodents.
2 0.8 TD.95078   TD.130345  
4 1.6 TD.92034 TD.110078   TD.03095
8 3.2 TD.92012 TD.03142    

* When added to natural ingredient diets, these water soluble food dyes offer a slight color tint. More intense color can be achieved at higher inclusion rates.
Ask a nutritionist about additional salt concentrations or color options.
These diets are grain-based, with no animal derived ingredients, and have a background sodium content of approx. 0.01-0.02% and a background chloride content of approx. 0.06-0.07%. The selected nutrient content of the diets are as follows: approximately 19% protein, 5% fat, 3% crude fiber, 0.86% Ca, 0.64% P, 0.72% K, and 0.15% Mg.
NaCl adjusted diets are often fed to dahl salt-sensitive/resistant (rapp) inbred rats. These rats are maintained on Teklad traditional diet 7034 (0.12% NaCl) within maximum security production facilities.

盐调节(天然成分)

玉米、小麦、豆粕等天然成分的钠含量较低。因此,这些成分可以用来制造一种缺乏钠的基础饮食。在这一基础日粮中,可以添加各种量的氯化钠盐(NaCl),其他成分也可以稍加调整,以保持相对稳定的营养状况(除钠和氯化物外)。下面是一系列受欢迎的调整NaCl饮食的例子。欲了解更多信息,请与我们联系。

公式实例
添加NaCl(%) 大约。NA(%) 无染料 红*染料 橙*染料 蓝*染料
NA缺乏 0.01-0.02 TD.90228 TD.08290    
可能的对照日粮:0.05%Na(0.1%NaCl)符合EST。最低钠需要量典型的啮齿动物日粮中含0.2%~0.4%Na(~0.5%-1%NaCl).
0.1 0.05 TD.94268   TD.07334  
0.49 0.2 TD.96208   TD.110765  
1 0.4 TD.90229      
用于研究啮齿类动物摄入过量钠的影响的饮食。
2 0.8 TD.95078   TD.130345  
4 1.6 TD.92034 TD.110078   TD.03095
8 3.2 TD.92012 TD.03142    

*将这些水溶性食物染料加入天然成分的饮食中,可提供轻微的色泽。在较高的包合率下可以获得更强烈的颜色。
向营养师询问额外的盐浓度或颜色选择。
这些饮食是以谷物为基础的,没有动物来源的成分,并且背景钠含量约为。0.01-0.02%,背景氯含量约为0.01-0.02%.0.06-0.07%。日粮的营养成分为:蛋白质约19%,脂肪5%,粗纤维3%,钙0.86%,磷0.64%,钾0.72%,镁0.15%。
食盐调节后的饲料通常喂给Dahl盐敏感/耐盐(Rapp)近交系大鼠.这些老鼠传统饮食7034(0.12%NaCl)在最大安全生产设施内。
上海金畔生物科技有限公司(www.jinpanbio.com)提供生命科学研究领域系列产品,包括生化试剂、诊断试剂、色谱标准品和实验仪器耗材。主营Lumiprobe Cy系列活性荧光染料;修饰性PEG(Laysan bio、NANOCS、Avanti等进口品牌PEG以及定制合成修饰性聚乙二醇、单分散小分量PEG);Sigma、Amresco、TCI、MP bio生化试剂;WAKO日本和光纯药、日本关东化学Kanto试剂、日本三菱、日本柴田科学SIBATA;Megazyme食品分析检测试剂盒、日本共立理化学;Research diets、Harlan饲料、Bio-Serv、日本CLEA Japan品牌的动物饲料;Oxoid、Nissui日水、日本荣研、BD difco、Himedia品牌微生物培养基;免疫诊断试剂包括:Bethyl抗体;Biolegend流式抗体、Abcam、CST、Santa Cruz抗体;Roche、TOYOBO、NEB品牌的酶;中检所、TRC、药典USP、EP、Reagecon标准品;耗材和仪器包括Whatman、日本Advantec滤膜、Millipore品牌的各种滤膜、滤器和柱子填料等、Hampton蛋白结晶试剂耗材、老鼠软管灌胃针、动物毛发记号笔、Labnet、Wheaton瓶子、Bio-Rad伯乐、康宁Corning、Axygen、Falcon 、Eppendorf、Nunc、Nalgene、Nest品牌的培养皿、培养板、离心机、离心管、移液枪及枪头等实验室常用仪器耗材。
上海金畔生物科技有限公司
服务热线:18301939375   QQ:3258089810    3259632176
Email:  info@jinpanbio.com
官网:http://www.jinpanbio.com

Harlan Teklad动物饲料 Harlan代理

Harlan Teklad动物饲料 Harlan代理
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
harlan是美国最大大的实验动物饲料生产商,产品销售遍布全世界
Harlan is a leading provider of essential, pre-clinical and non-clinical contract research, research models, lab animal diets, and services. Our focus is on providing customers with products and services to optimize the discovery and safety of new medicines and compounds.

CA.170481 AIN-76A Purified Diet AIN-76A 纯化饲料 50kg 询价 harlan
TD.94045 AIN-93G Purified Diet AIN-93G 纯化饲料 50kg 询价 harlan
TD.94048 AIN-93M Purified Diet AIN-93M 纯化饲料 50kg 询价 harlan
TD.94096 version of AIN-76A suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-76A 饲料 维生素含量增加 50kg 询价 harlan
TD.97184 version of AIN-93G suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93G 饲料 维生素含量增加 50kg 询价 harlan
TD.00102 version of AIN-93M suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93M 饲料 维生素含量增加 50kg 询价 harlan
TD.95092 modification of AIN-93G where soybean oil is replaced with corn oil. AIN-93G饲料 豆油改为玉米油 50kg 询价 harlan
TD.06414 Adjusted Calories Diet (60/Fat) 卡路里调控饲料 60%脂肪 50kg 询价 harlan
TD.06415 Adjusted Calories Diet (45/Fat) 卡路里调控饲料 45%脂肪 50kg 询价 harlan
TD.03584 35% Lard Diet (Adj., No C) 35%猪油饲料 50kg 询价 harlan
TD.93075 Adjusted Calories Diet (55/fat) 卡路里调控饲料 55%脂肪 50kg 询价 harlan
TD.95217 Adjusted Fat Diet 脂肪控饲料 50kg 询价 harlan
TD.96132 Adjusted Fat Diet 脂肪控饲料 50kg 询价 harlan
TD.88137 Adjusted Kcal Diet (42% from fat 大卡调控饲料 42%脂肪 50kg 询价 harlan
TD.08811 45% Kcal Fat Diet (21% MF, 2% SBO) 45%大卡脂肪饲料 42%脂肪 50kg 询价 harlan
TD.06416 Adjusted Calories Diet (10/Fat) (a possible control for TD.06415 & TD.06414 listed above) 卡路里调控饲料 10%脂肪 50kg 询价 harlan
TD.08810 Low Glycemic Control Diet 低血糖饲料 50kg 询价 harlan
TD.96355 Ketogenic Diet 生酮饲料 50kg 询价 harlan
TD.84224 Essential Fatty Acid Deficient Diet 必须氨基酸缺损饲料 50kg 询价 harlan
TD.88137 Adjusted Calories Diet (42% from fat) 卡路里调控饲料 42%脂肪 50kg 询价 harlan
TD.88051 Cocoa Butter and Purina Chow Diet 椰子油和Purina Chow饲料 50kg 询价 harlan
TD.90221 Cocoa Butter Diet with 75% Purina Mouse (5015) 50kg 询价 harlan
TD.94059 5015, Cocoa Butter, Chol., etc. (excludes cholate) 50kg 询价 harlan
TD.02028 Atherogenic Rodent Diet (1.25% Chol. & 0.5% Cholic Acid) 50kg 询价 harlan
TD.01383 2018 + 2% Cholesterol 50kg 询价 harlan
TD.86143 Vitamin A Deficient Diet 50kg 询价 harlan
TD.89123 Vitamin D Deficient Diet 50kg 询价 harlan
TD.88163 Vitamin E Deficient Diet 50kg 询价 harlan
TD.95247 Folic Acid Deficient Diet 50kg 询价 harlan
TD.80396 Iron Deficient Diet 50kg 询价 harlan
TD.85419 Zinc Deficient Diet 50kg 询价 harlan
TD.88239 Potassium Deficient Diet 50kg 询价 harlan
TD.95027 Low Calcium Diet (0.4% P) 50kg 询价 harlan
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P) 50kg 询价 harlan
TD.92163 Selenium Deficient Diet 50kg 询价 harlan
TD.95125 Iodine Deficient (0.15% PTU) 50kg 询价 harlan
TD.93328 Protein Free Diet 50kg 询价 harlan
TD.90016 6% Protein Diet 50kg 询价 harlan
TD.91352 20% Protein Diet 50kg 询价 harlan
TD.90018 40% Protein Diet 50kg 询价 harlan
TD.89247 60% Fructose Diet 50kg 询价 harlan
TD.86489 Diet with Adjusted Sucrose/Cornstarch 50kg 询价 harlan
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P) 50kg 询价 harlan
TD.98090 70% Carbohydrate Diet 50kg 询价 harlan
TD.96355 Ketogenic Diet (almost no carbohydrate) 50kg 询价 harlan
TD.99366 Amino Acid Diet 50kg 询价 harlan
TD.90262 Methionine & Choline Deficient Diet 50kg 询价 harlan
TD.00434 Folic Acid Deficient Diet 50kg 询价 harlan
TD.99386 No Lysine AA Diet 50kg 询价 harlan
TD.90228 Sodium Deficient Diet 50kg 询价 harlan
TD.96208 0.49% NaCl Diet 50kg 询价 harlan
TD.90229 1% NaCl Diet 50kg 询价 harlan
TD.92034 4% NaCl Diet 50kg 询价 harlan
TD.92012 8% NaCl Diet 50kg 询价 harlan
TD.01306 Rodent Diet (2018 + 625 doxycycline) 50kg 询价 harlan
TD.98186 Rodent Diet (7012 + 200 doxycycline) 50kg 询价 harlan
TD.92033 Swine Diet (15% Lard, 1.2% Cholesterol) 50kg 询价 harlan
TD.92052 Swine Diet (15% Lard, 1.5% Cholesterol) 50kg 询价 harlan
TD.93296 Swine Diet (15% Lard, 2% Cholesterol) 50kg 询价 harlan
CA.40060 Teklad Vitamin Mix 50kg 询价 harlan
CA.40077 AIN-76A Vitamin Mix 50kg 询价 harlan
TD.94047 AIN-93 Vitamin Mix 50kg 询价 harlan
CA.170915 AIN-76 Mineral Mix 50kg 询价 harlan
TD.94046 AIN-93G Mineral Mix 50kg 询价 harlan
TD.94049 AIN-93M Mineral Mix 50kg 询价 harlan
TD.79055 Calcium & Phosphorus Deficient Mineral Mixed based on AIN-76 50kg 询价 harlan
TD.98057 Calcium & Phosphorus Deficient Mineral Mixed based on AIN-93 50kg 询价 harlan

上海金畔生物科技有限公司(www.jinpanbio.com)提供生命科学研究领域系列产品,包括生化试剂、诊断试剂、色谱标准品和实验仪器耗材。主营Lumiprobe Cy系列活性荧光染料;修饰性PEG(Laysan bio、NANOCS、Avanti等进口品牌PEG以及定制合成修饰性聚乙二醇、单分散小分量PEG);Sigma、Amresco、TCI、MP bio生化试剂;WAKO日本和光纯药、日本关东化学Kanto试剂、日本三菱、日本柴田科学SIBATA;Megazyme食品分析检测试剂盒、日本共立理化学;Research diets、Harlan饲料、Bio-Serv、日本CLEA Japan品牌的动物饲料;Oxoid、Nissui日水、日本荣研、BD difco、Himedia品牌微生物培养基;免疫诊断试剂包括:Bethyl抗体;Biolegend流式抗体、Abcam、CST、Santa Cruz抗体;Roche、TOYOBO、NEB品牌的酶;中检所、TRC、药典USP、EP、Reagecon标准品;耗材和仪器包括Whatman、日本Advantec滤膜、Millipore品牌的各种滤膜、滤器和柱子填料等、Hampton蛋白结晶试剂耗材、老鼠软管灌胃针、动物毛发记号笔、Labnet、Wheaton瓶子、Bio-Rad伯乐、康宁Corning、Axygen、Falcon 、Eppendorf、Nunc、Nalgene、Nest品牌的培养皿、培养板、离心机、离心管、移液枪及枪头等实验室常用仪器耗材。
上海金畔生物科技有限公司
服务热线:18301939375   QQ:3258089810    3259632176
Email:  info@jinpanbio.com
官网:http://www.jinpanbio.com

Harlan定制研究饲料 Diet ingredients

Harlan定制研究饲料 Diet ingredients
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
You may want to prepare your own diet at your research site or facility, and if that is the case, you depend on the ingredients being of the highest quality. Envigo can provide you with many of the same ingredients used to produce our advanced Teklad custom research diets so you can develop your own formula. And as always, our nutritional experts are here to help you make the best decisions for your ingredients and ultimate formulation.
Our ingredients
We offer several ingredients for individual sale so that you can develop your own blends.
“VFT” casein

  • “Vitamin-free” test casein (alcohol-extracted) is best suited for purified test diet formulas where fat or vitamin content needs to be precisely controlled
  • The reduced levels of many vitamins in VFT casein make it the preferred protein source for many vitamin studies. Thus, the nickname “Vitamin-free” was given to the extracted casein many years ago

Vitamin mixes

  • The common vitamin mixes shown below use sucrose or corn starch as a carrier
  • Customized vitamin mixes may use cellulose if a non-nutritive carrier is necessary
  • Vitamin mixes are formulated with a diet inclusion rate in mind. Using more or less than recommended could impair the health of your laboratory animal
  • For those preparing their own diets, vitamin premixes are an efficient way to add vitamins to a diet
  • Vitamin mixes should be stored at 4 degrees celsius or lower upon receipt. Storage at –20 degrees celsius is recommended if the mix will be used beyond 1 month
  • Minimum order is 500 g for both stock and custom vitamin mixes
  • Our available vitamin mixes are commonly used in diets, and are available from stock
  • Vitamin mixes are shipped within a few days of order

Our Formula examples

  • CA.40060     Teklad vitamin mix
  • CA.40077     AIN-76A vitamin mix
  • TD.94047     AIN-93 vitamin mix

Mineral mixes

  • The common mineral mixes shown below as examples use sucrose as a carrier
  • Customized mineral mixes could use cellulose or no carrier if a non-nutritive carrier is necessary
  • Our mineral mixes are formulated with a diet inclusion rate in mind. Using more or less than recommended could impair the health of the animal
  • For those preparing their own diets, mineral premixes are an efficient way to add minerals to a diet
  • Mineral mixes should be stored in a dry cool environment and used within a year of receipt. The minimum order is 500 g for both stock and custom mineral mixes
  • These mineral mixes are commonly used in diets, and are available from stock
  • Our mineral mixes are shipped within a few days of order

Formula examples:

  • CA.170915    AIN-76 mineral mix
  • TD.94046      AIN-93G mineral mix
  • TD.94049      AIN-93M mineral mix

Other mixes (may or may not be available from stock):

  • TD.83171     Vitamin mix without A, D, E, choline
  • TD.81062     Iron deficient mineral mix based on AIN-76A
  • TD.79055     Calcium and phosphorus deficient mineral mixed based on AIN-76
  • TD.98057     Calcium and phosphorus deficient mineral mixed based on AIN-93
  • CA.170760   Rogers-Harper mineral mix

你可能想要在你的研究地点或设施准备你自己的饮食,如果是这样的话,你取决于成分是最高的质量。Envigo可以为您提供许多相同的成分,用于生产我们先进的特克拉德定制研究饮食,以便您可以开发自己的配方。和往常一样,我们的营养专家在这里帮助您为您的配料和最终配方做出最佳决定。
我们的配料
我们提供几个配料供个人销售,以便您可以开发自己的混合。
“VFT”酪蛋白

  • “无维生素”测试酪蛋白(酒精提取)最适合于那些需要精确控制脂肪或维生素含量的纯正试验饮食配方。
  • VFT酪蛋白中许多维生素含量的降低使得它成为许多维生素研究的首选蛋白质来源。因此,“无维生素”的绰号是在许多年前给提取出来的酪蛋白起的。

维生素混合物

  • 以下常见的维生素混合物使用蔗糖或玉米淀粉作为载体。
  • 定制的维生素混合物可能使用纤维素,如果非营养载体是必要的。
  • 维生素混合物的制定考虑到了饮食中的包容率。多用或少用会损害你的实验动物的健康。
  • 对于那些自己准备饮食的人来说,维生素预混剂是向饮食中添加维生素的一种有效方法。
  • 维生素混合物应储存在4摄氏度或更低的接收。如果使用时间超过1个月,建议使用摄氏-20度。
  • 库存和定制维生素混合物的最低订购量为500克。
  • 我们可用的维生素混合物通常用于饮食,并可从库存中获得。
  • 维生素混合物在订购后几天内发货。

我们的公式示例

  • CA.40060特克拉德维生素混合物
  • CA.40077AIN-76A维生素混合物
  • TD.94047AIN-93维生素混合物

矿物混合物

  • 下面所示的常见矿物混合物是以蔗糖为载体的。
  • 如果需要非营养的载体,定制的矿物混合物可以使用纤维素,也可以不使用载体。
  • 我们的矿物质混合物是根据饮食包容率来制定的。多用或少用会损害动物的健康。
  • 对于那些自己准备饮食的人来说,矿物预混料是向饮食中添加矿物质的有效方法。
  • 矿物混合物应存放在干燥、凉爽的环境中,并在收到后一年内使用。库存和自定义矿物混合物的最低订购量为500克。
  • 这些矿物混合物通常用于饮食,并可从库存中获得。
  • 我们的矿物混合物在订货后几天内装运。

公式示例:

  • CA.170915AIN-76矿物混合物
  • TD.94046AIN-93g矿物混合物
  • TD.94049AIN-9300万矿物混合物

其他混合材料(可能从库存中获得,也可能无法从库存中获得):

  • TD.83171不含A,D,E,胆碱的维生素混合物
  • TD.81062基于AIN-76A的缺铁矿物配料
  • TD.79055AIN-76混合钙磷缺乏矿物
  • TD.98057AIN-93混合钙磷缺乏矿物
  • CA.170760罗杰斯-哈珀矿物混合物

Harlan TD.81062 说明书 Iron deficient mineral mix based on AIN-76A

Harlan TD.81062 说明书 Iron deficient mineral mix based on AIN-76A
Harlan Teklad动物饲料
Harlan代理
欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。
Formula
Calcium Phosphate, dibasic   500.0
Sodium Chloride   74.0
Potassium Citrate, monohydrate   220.0
Potassium Sulfate   52.0
Magnesium Oxide   24.0
Manganous Carbonate   3.5
Zinc Carbonate   1.6
Cupric Carbonate   0.3
Potassium Iodate    0.01
Sodium Selenite, pentahydrate   0.01
Chromium Potassium Sulfate, dodecahydrate    0.55
Sucrose, fine ground    124.03
Key Features
+ Mineral Mix
+ Modified From AIN-76
+ Iron Deficient
+ Rodent
Key Planning Information
+ Products are made fresh to order
+ Lead time 2 weeks
+Store in cool, dry conditions
+ Use within 12 months (applicable to most mixes)
+ Box labeled with product name,
manufacturing date, and lot number
Product Specific Information
+ Powder
+ Minimum order 500 grams
Footnote
This modification of the AIN-76 mineral mix (170915) uses a reagent
grade/pretested CaHPO4 to help reduce the inherent background iron
contributed from this compound. The mineral mix itself is tested for iron
content prior to use.
Options (fees will apply)
+ Rush order (pending availability)
+ Vacuum packaging (1 and 2 Kg)
CA.170481 AIN-76A Purified Diet AIN-76A 纯化饲料 50kg
TD.94045 AIN-93G Purified Diet AIN-93G 纯化饲料 50kg
TD.94048 AIN-93M Purified Diet AIN-93M 纯化饲料 50kg
TD.94096 version of AIN-76A suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-76A 饲料 维生素含量增加 50kg
TD.97184 version of AIN-93G suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93G 饲料 维生素含量增加 50kg
TD.00102 version of AIN-93M suitable for irradiation (vitamin levels are increased) 适合辐照的AIN-93M 饲料 维生素含量增加 50kg
TD.95092 modification of AIN-93G where soybean oil is replaced with corn oil. AIN-93G饲料 豆油改为玉米油 50kg
TD.06414 Adjusted Calories Diet (60/Fat) 卡路里调控饲料 60%脂肪 50kg
TD.06415 Adjusted Calories Diet (45/Fat) 卡路里调控饲料 45%脂肪 50kg
TD.03584 35% Lard Diet (Adj., No C) 35%猪油饲料 50kg
TD.93075 Adjusted Calories Diet (55/fat) 卡路里调控饲料 55%脂肪 50kg
TD.95217 Adjusted Fat Diet 脂肪控饲料 50kg
TD.96132 Adjusted Fat Diet 脂肪控饲料 50kg
TD.88137 Adjusted Kcal Diet (42% from fat 大卡调控饲料 42%脂肪 50kg
TD.08811 45% Kcal Fat Diet (21% MF, 2% SBO) 45%大卡脂肪饲料 42%脂肪 50kg
TD.06416 Adjusted Calories Diet (10/Fat) (a possible control for TD.06415 &
TD.06414 listed above) 卡路里调控饲料 10%脂肪 50kg
TD.08810 Low Glycemic Control Diet 低血糖饲料 50kg
TD.96355 Ketogenic Diet 生酮饲料 50kg
TD.84224 Essential Fatty Acid Deficient Diet 必须氨基酸缺损饲料 50kg
TD.88137 Adjusted Calories Diet (42% from fat) 卡路里调控饲料 42%脂肪 50kg
TD.88051 Cocoa Butter and Purina Chow Diet 椰子油和Purina Chow饲料 50kg
TD.90221 Cocoa Butter Diet with 75% Purina Mouse (5015)   50kg
TD.94059 5015, Cocoa Butter, Chol., etc. (excludes cholate)   50kg
TD.02028 Atherogenic Rodent Diet (1.25% Chol. & 0.5% Cholic Acid) 50kg
TD.01383 2018 + 2% Cholesterol   50kg
TD.86143 Vitamin A Deficient Diet 50kg
TD.89123 Vitamin D Deficient Diet 50kg
TD.88163 Vitamin E Deficient Diet 50kg
TD.95247 Folic Acid Deficient Diet 50kg
TD.80396 Iron Deficient Diet   50kg
TD.85419 Zinc Deficient Diet   50kg
TD.88239 Potassium Deficient Diet 50kg
TD.95027 Low Calcium Diet (0.4% P) 50kg
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P) 50kg
TD.92163 Selenium Deficient Diet   50kg
TD.95125 Iodine Deficient (0.15% PTU) 50kg
TD.93328 Protein Free Diet   50kg
TD.90016 6% Protein Diet   50kg
TD.91352 20% Protein Diet   50kg
TD.90018 40% Protein Diet   50kg
TD.89247 60% Fructose Diet   50kg
TD.86489 Diet with Adjusted Sucrose/Cornstarch   50kg
TD.96348 Diet (20% Lactose, 2% Ca, 1.25% P)   50kg
TD.98090 70% Carbohydrate Diet   50kg
TD.96355 Ketogenic Diet (almost no carbohydrate)50kg
TD.99366 Amino Acid Diet   50kg
TD.90262 Methionine & Choline Deficient Diet 50kg
TD.00434 Folic Acid Deficient Diet   50kg
TD.99386 No Lysine AA Diet   50kg
TD.90228 Sodium Deficient Diet   50kg
TD.96208 0.49% NaCl Diet   50kg
TD.90229 1% NaCl Diet   50kg
TD.92034 4% NaCl Diet   50kg
TD.92012 8% NaCl Diet   50kg
TD.01306 Rodent Diet (2018 + 625 doxycycline)   50kg
TD.98186 Rodent Diet (7012 + 200 doxycycline)   50kg
TD.92033 Swine Diet (15% Lard, 1.2% Cholesterol) 50kg
TD.92052 Swine Diet (15% Lard, 1.5% Cholesterol) 50kg
TD.93296 Swine Diet (15% Lard, 2% Cholesterol)   50kg
CA.40060 Teklad Vitamin Mix   50kg
CA.40077 AIN-76A Vitamin Mix   50kg
TD.94047 AIN-93 Vitamin Mix   50kg
CA.170915 AIN-76 Mineral Mix   50kg
TD.94046 AIN-93G Mineral Mix   50kg
TD.94049 AIN-93M Mineral Mix   50kg