磷酸化ALK (Tyr1078) (D28B4) 兔单克隆抗体
Phospho-ALK (Tyr1078) (D28B4) Rabbit mAb
详细描述:
Species predicted to react based on 100% sequence homology: Mouse, Rat。只有当Tyr1078(相当于NPM-ALK中的Tyr138)磷酸化时,磷酸化ALK (Tyr1078) (D28B4) 兔单抗能够识别内源性水平的ALK。该抗体可能与其他过量表达的磷酸化酪氨酸激酶如EGFR和Src,发生交叉反应。该单克隆抗体是通过用合成磷酸肽免疫动物而制备的,该合成磷酸肽是人ALK蛋白Tyr1078附近的残基。Phospho-ALK (Tyr1078) (D28B4) Rabbit mAb recognizes endogenous levels of ALK only when phosphorylated at Tyr1078, which is equivalent to Tyr138 of NPM-ALK. This antibody may cross-react weakly with other overexpressed phospho-tyrosine kinases such as EGFR and Src.Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1078 of human ALK protein.
Species predicted to react based on 100% sequence homology: Mouse, Rat。只有当Tyr1078(相当于NPM-ALK中的Tyr138)磷酸化时,磷酸化ALK (Tyr1078) (D28B4) 兔单抗能够识别内源性水平的ALK。该抗体可能与其他过量表达的磷酸化酪氨酸激酶如EGFR和Src,发生交叉反应。该单克隆抗体是通过用合成磷酸肽免疫动物而制备的,该合成磷酸肽是人ALK蛋白Tyr1078附近的残基。Phospho-ALK (Tyr1078) (D28B4) Rabbit mAb recognizes endogenous levels of ALK only when phosphorylated at Tyr1078, which is equivalent to Tyr138 of NPM-ALK. This antibody may cross-react weakly with other overexpressed phospho-tyrosine kinases such as EGFR and Src.Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1078 of human ALK protein.
应用范围:W IP; 反应种属:Human; 灵敏度:Endogenous; MW (kDa):220 (ALK), 80 (NPM-ALK); Isotype:Rabbit IgG; 标记:无标记。
货号 | 产品名称 | 品牌 | 购买 |
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货号 | 名称 | 单位 | 购买 |
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12127S | 磷酸化ALK (Tyr1078) (D28B4) 兔单克隆抗体 | 100µl | 咨询客服 |