磷酸化EGF 受体 (Tyr1068) (1H12) 小鼠单克隆抗体
Phospho-EGF Receptor (Tyr1068) (1H12) Mouse mAb
详细描述:
磷酸化的EGFR (Tyr1068)的小鼠源抗体(1H12)仅在Tyr1068位点被磷酸化后才能检测到内源EGFR的水平。本抗体不识别其它位点磷酸化的EGFR,但可能与激活的ErbB家族的其它蛋白发生交叉反应,并在石蜡包埋组织的平滑肌中有非特异着色。单克隆抗体通过用合成磷酸化多肽免疫动物得到,该磷酸化多肽是根据人的EGFR蛋白Tyr1068附近的氨基酸序列合成的。Phospho-EGF Receptor (Tyr1068) (1H12) Mouse mAb detects endogenous levels of EGF receptor only when phosphorylated at Tyr1068. This antibody does not recognize EGF receptor phosphorylated at other sites, but may cross-react with other activated ErbB family members. Non-specific staining of smooth muscle may be observed in paraffin-embedded tissues. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1068 of human EGF receptor.
磷酸化的EGFR (Tyr1068)的小鼠源抗体(1H12)仅在Tyr1068位点被磷酸化后才能检测到内源EGFR的水平。本抗体不识别其它位点磷酸化的EGFR,但可能与激活的ErbB家族的其它蛋白发生交叉反应,并在石蜡包埋组织的平滑肌中有非特异着色。单克隆抗体通过用合成磷酸化多肽免疫动物得到,该磷酸化多肽是根据人的EGFR蛋白Tyr1068附近的氨基酸序列合成的。Phospho-EGF Receptor (Tyr1068) (1H12) Mouse mAb detects endogenous levels of EGF receptor only when phosphorylated at Tyr1068. This antibody does not recognize EGF receptor phosphorylated at other sites, but may cross-react with other activated ErbB family members. Non-specific staining of smooth muscle may be observed in paraffin-embedded tissues. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1068 of human EGF receptor.
应用范围:W IP IHC-P; 反应种属:Human,Rat,Monkey; 灵敏度:Endogenous; MW (kDa):175; Isotype:Mouse IgG1; 标记:无标记。
货号 | 产品名称 | 品牌 | 购买 |
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货号 | 名称 | 单位 | 购买 |
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2236L | 磷酸化EGF 受体 (Tyr1068) (1H12) 小鼠单克隆抗体 | 300µl | 咨询客服 |
2236S | 磷酸化EGF 受体 (Tyr1068) (1H12) 小鼠单克隆抗体 | 100µl | 咨询客服 |