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HSC70/HSP70 热休克蛋白
热休克蛋白 HSP70 家族包含 66-78 kDa 多种大小不等的同源物。研究最多的 HSP70 成员有以下几种:细胞内应激诱导的 HSC70(HSP70),构成细胞质的 HSC70(HSP73),ER 定位的 BiP(GRP78)等。HSP70 家族成员包含高度保守的 ATP 酶N-末端和C-末端蛋白结合域。在 HSP40 作用下,HSP70 与肽结合,刺激 HSP70 的 ATP 酶活性,促进 ATP 水解,增强肽结合能力。HSP70 核苷酸与底物结合调节新合成的蛋白折叠,将折叠错误或变性的蛋白重新折叠,指挥跨膜蛋白的转运,抑制蛋白质聚集,通过蛋白酶解途径降解目标蛋白,从而在神经退行性疾病的发病机制中发挥着重要的作用,其功能和作用机制的进一步阐明则对治疗和预防神经退行性疾病具有重要的意义。
抗体
产品编号 |
产品名称 |
规格 |
特异性 |
应用 |
ADI-SPA-758-E |
HSC70/HSP70 (fish), pAb |
100 μL |
鱼 |
WB |
ADI-SPA-757-D |
HSC70/HSP70, pAb |
50 μg |
人、小鼠、大鼠、牛、狗、鸡、果蝇、猴子、猪、植物、兔子、羊、酵母 |
IHC/WB |
ADI-SPA-757-F |
200 μg |
|||
ADI-SPA-757-J |
1 mg |
|||
ALX-804-067-R050 |
HSC70, mAb (13D3) |
50 μL |
人、小鼠、大鼠、猴子、猫 |
IF/IHC/IP/WB |
ADI-SPA-822-D |
HSC70/HSP70, mAb (BB70) |
50 μg |
人、小鼠、大鼠、果蝇、昆虫 ( 家蝇 )、兔子、海绵、酵母 |
IHC/IP/WB |
ADI-SPA-822-F |
200 μg |
|||
ADI-SPA-815-D |
HSC70/HSP73, mAb (1B5) |
50 μg |
人、小鼠、大鼠、牛、狗、 鸡、豚鼠、仓鼠、猴子、猪、兔子、羊、龟 |
ELISA/FC/ICC/IHC(PS)/IP/WB |
ADI-SPA-815-F |
200 μg |
|||
ADI-SPA-815-J |
1 mg |
|||
ADI-SPA-815PE-E |
HSC70/HSP73, mAb (1B5) (PE conjugate) |
100 μg |
人、小鼠、大鼠、牛、狗、鸡、仓鼠、豚鼠、猴子、兔子、猪、羊 |
FC |
ADI-SPA-815-488-E |
HSC70/HSP73, mAb (1B5) (DyLight ™ 488 conjugate) |
100 μg |
人、小鼠、大鼠、牛、 狗、 鸡、豚鼠、 仓鼠、、猴子、猪、兔子、羊 |
FC |
ADI-SPA-757-F |
||||
ADI-SPA-820AP-D |
HSC70/HSP70, mAb (N27F3-4) (AP conjugate) |
50 μL |
人、小鼠、大鼠、牛、狗、 鸡、鱼 |
WB |
ADI-SPA-820AP-F |
200 μL |
|||
ADI-SPA-820PE-D |
HSC70/HSP70, mAb (N27F3-4) (PE conjugate) |
50 μg |
人、小鼠、大鼠、牛、 狗、 鸡、鱼 |
FC |
ADI-SPA-820PE-F |
200 μg |
|||
ADI-SPA-820-488-E |
HSC70/HSP70, mAb (N27F3-4) (DyLight™ 488 conjugate) |
100 μg |
人、小鼠、鲟、牛、狗、鸡、鱼 |
FC |
蛋白
产品编号 |
产品名称 |
规格 |
ADI-SPP-751-D |
HSC70/HSP73 (bovine), (recombinant) |
50 μg |
ADI-SPP-751-F |
200 μg |
|
ADI-SPP-752-D |
HSC70/HSP73 (ATPase fragment) (bovine), (recombinant) |
50 μg |
ADI-SPP-752-F |
200 μg |
|
ADI-SPP-761-E |
HSC70/HSP73(bovine), (recombinant)(biotin conjugate) |
100 μg |
ALX-201-216-C025 |
Hip (human), (recombinant) |
25 μg |
ALX-201-218-C025 |
Hop(human), (recombinant) |
25 μg |
ADI-APR-400-0050 |
BAG-1M(human), (recombinant) (His-tag) |
50 μg |
ADI-APR-400-0200 |
200 μg |
|
ADI-APR-401-0050 |
BAG-1S(human), (recombinant)(His-tag) (GST-tag) |
50 μg |
ADI-APR-401-0200 |
200 μg |
试剂套装
产品编号 |
产品名称 |
应用 |
规格 |
BML-TK4000-0001 |
Microtubule-associated Protein Tau detection pack |
IHC/WB |
1 Pack |
产品编号 | 产品名称 | 产品规格 | 产品等级 |
ADI-SPA-758-E | HSC70/HSP70 (fish), pAb 热休克同源蛋白70/热休克蛋白70 (鱼), 多抗 |
100 μL | – |
ADI-SPA-757-D | HSC70/HSP70, pAb 热休克同源蛋白70/热休克蛋白70, 多抗 |
50 μg | – |
ADI-SPA-757-F | HSC70/HSP70, pAb 热休克同源蛋白70/热休克蛋白70, 多抗 |
200 μg | – |
ADI-SPA-757-J | HSC70/HSP70, pAb 热休克同源蛋白70/热休克蛋白70, 多抗 |
1 mg | – |
ALX-804-067-R050 | HSC70, mAb (13D3) | 50 μL | |
ADI-SPA-822-D | HSC70/HSP70, mAb (BB70) | 50 μg | |
ADI-SPA-822-F | HSC70/HSP70, mAb (BB70) | 200 μg | |
ADI-SPA-815-D | HSC70/HSP73, mAb (1B5) | 50 μg | |
ADI-SPA-815-F | HSC70/HSP73, mAb (1B5) | 200 μg | |
ADI-SPA-815-J | HSC70/HSP73, mAb (1B5) | 1 mg | |
ADI-SPA-815PE-E | HSC70/HSP73, mAb (1B5) (PE conjugate) | 100 μg | |
ADI-SPA-815-488-E | HSC70/HSP73, mAb (1B5) (DyLight ™ 488 conjugate) | 100 μg | |
ADI-SPA-757-F | HSC70/HSP73, mAb (1B5) (DyLight ™ 488 conjugate) | 100 μg | |
ADI-SPA-820AP-D | HSC70/HSP70, mAb (N27F3-4) (AP conjugate) | 50 μL | |
ADI-SPA-820AP-F | HSC70/HSP70, mAb (N27F3-4) (AP conjugate) | 200 μL | |
ADI-SPA-820PE-D | HSC70/HSP70, mAb (N27F3-4) (PE conjugate) | 50 μg | |
ADI-SPA-820PE-F | HSC70/HSP70, mAb (N27F3-4) (PE conjugate) | 200 μg | |
ADI-SPA-820-488-E | HSC70/HSP70, mAb (N27F3-4) (DyLight™ 488 conjugate) | 100 μg | |
ADI-SPP-751-D | HSC70/HSP73 (bovine), (recombinant) | 50 μg | |
ADI-SPP-751-F | HSC70/HSP73 (bovine), (recombinant) | 200 μg | |
ADI-SPP-752-D | HSC70/HSP73 (ATPase fragment) (bovine), (recombinant) | 50 μg | |
ADI-SPP-752-F | HSC70/HSP73 (ATPase fragment) (bovine), (recombinant) | 200 μg | |
ADI-SPP-761-E | HSC70/HSP73(bovine), (recombinant)(biotin conjugate) | 100 μg | |
ALX-201-216-C025 | Hip (human), (recombinant) | 25 μg | |
ALX-201-218-C025 | Hop(human), (recombinant) | 25 μg | |
ADI-APR-400-0050 | BAG-1M(human), (recombinant) (His-tag) | 50 μg | |
ADI-APR-400-0200 | BAG-1M(human), (recombinant) (His-tag) | 200 μg | |
ADI-APR-401-0050 | BAG-1S(human), (recombinant)(His-tag) (GST-tag) | 50 μg | |
ADI-APR-401-0200 | BAG-1S(human), (recombinant)(His-tag) (GST-tag) | 200 μg | |
BML-TK4000-0001 | Microtubule-associated Protein Tau detection pack | 1 Pack |