产品基本信息

货号：36705

产品名称：脱氧胆酸-iFluor 647 缀合物

规格：1mg

储存条件：-15℃避光防潮

保质期：24个月

产品物理化学光谱特性

分子量：1253.63

外观：固体

溶剂：DMSO

激发波长(nm)：656

发射波长(nm)：670

产品介绍

脱氧胆酸，也称为胆酸，是一种胆汁酸。脱氧胆酸-iFluor 647 缀合物是脱氧胆酸的红色荧光衍生物。它是一种 iFluor 647 标记的胆汁酸衍生物，与脱氧胆酸的细胞结合和吸收特性密切相关。它是一种二价“单极”阴离子荧光胆汁盐类似物，在肝细胞水平上研究脱氧胆酸的细胞机制提供帮助。脱氧胆酸-iFluor 647 缀合物是具有强烈蓝色或绿色荧光的胆汁酸转运的工具，因为他具有强烈的红色荧光能够与蓝色或绿色荧光分离。脱氧胆酸是次级胆汁酸之一，是肠道细菌的代谢副产物。肝脏分泌的两种主要胆汁酸是胆酸和鹅去氧胆酸。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的iFluor系列产品。 

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参考文献

Cationic nanoparticles self-assembled from amphiphilic chitosan derivatives containing poly(amidoamine) dendrons and deoxycholic acid as a vector for co-delivery of doxorubicin and gene.
Authors: Chen, Shanshan and Deng, Junjie and Zhang, Li-Ming
Journal: Carbohydrate polymers (2021): 117706

Cholic acid and deoxycholic acid induce skeletal muscle atrophy through a mechanism dependent on TGR5 receptor.
Authors: Abrigo, Johanna and Gonzalez, Francisco and Aguirre, Francisco and Tacchi, Franco and Gonzalez, Andrea and Meza, María Paz and Simon, Felipe and Cabrera, Daniel and Arrese, Marco and Karpen, Saul and Cabello-Verrugio, Claudio
Journal: Journal of cellular physiology (2021): 260-272

Commentary on Alternative Cosmetic and Medical Applications of Injectable Deoxycholic Acid.
Authors: Hausauer, Amelia K
Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (2021)

Deoxycholic Acid Upregulates Serum Golgi Protein 73 through Activating NF-κB Pathway and Destroying Golgi Structure in Liver Disease.
Authors: Yang, Danli and Yao, Mingjie and Yan, Ying and Liu, Yanna and Wen, Xiajie and Chen, Xiangmei and Lu, Fengmin
Journal: Biomolecules (2021)

Deoxycholic Acid and Lithocholic Acid Alleviate Liver Injury and Inflammation in Mice with Klebsiella pneumoniae-Induced Liver Abscess and Bacteremia.
Authors: Zheng, Yahong and Yue, Chengcheng and Zhang, Hui and Chen, Haoran and Liu, Yanyan and Li, Jiabin
Journal: Journal of inflammation research (2021): 777-789

Deoxycholic Acid-Induced Gut Dysbiosis Disrupts Bile Acid Enterohepatic Circulation and Promotes Intestinal Inflammation.
Authors: Xu, Mengque and Cen, Mengsha and Shen, Yuqin and Zhu, Yubin and Cheng, Fangli and Tang, Linlin and Hu, Weiling and Dai, Ning
Journal: Digestive diseases and sciences (2021): 568-576

Deoxycholic acid activates and sensitizes vagal nociceptive afferent C-fibers in guinea pig esophagus.
Authors: Yu, Xiaoyun and Hu, Youtian and Yu, Mingwei and Undem, Bradley J and Yu, Shaoyong
Journal: American journal of physiology. Gastrointestinal and liver physiology (2021): G149-G156

Deoxycholic acid as a molecular scaffold for tyrosyl-DNA phosphodiesterase 1 inhibition: A synthesis, structure-activity relationship and molecular modeling study.
Authors: Salomatina, Oksana V and Popadyuk, Irina I and Zakharenko, Alexandra L and Zakharova, Olga D and Chepanova, Arina A and Dyrkheeva, Nadezhda S and Komarova, Nina I and Reynisson, Jóhannes and Anarbaev, Rashid O and Salakhutdinov, Nariman F and Lavrik, Olga I and Volcho, Konstantin P
Journal: Steroids (2021): 108771

Deoxycholic acid enhancement of lymphocyte migration through direct interaction with the intestinal vascular endothelium.
Authors: Shibuya, Naoki and Higashiyama, Masaaki and Akita, Yoshihiro and Shirakabe, Kazuhiko and Ito, Suguru and Nishii, Shin and Mizoguchi, Akinori and Inaba, Kenichi and Tanemoto, Rina and Sugihara, Nao and Hanawa, Yoshinori and Wada, Akinori and Horiuchi, Kazuki and Yoshikawa, Kenichi and Kurihara, Chie and Okada, Yoshikiyo and Watanabe, Chikako and Komoto, Shunsuke and Tomita, Kengo and Saruta, Masayuki and Hokari, Ryota
Journal: Journal of gastroenterology and hepatology (2021)

Deoxycholic acid induces proinflammatory cytokine production by model oesophageal cells via lipid rafts.
Authors: Quilty, Francis and Freeley, Michael and Gargan, Siobhan and Gilmer, John and Long, Aideen
Journal: The Journal of steroid biochemistry and molecular biology (2021): 105987