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iFluor 488-刀豆蛋白A(ConA)缀合物
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货号 | 25580 | 存储条件 | 在零下15度以下保存, 避免光照 |
| 规格 | 1 mg | 价格 | 1176 | |
| Ex (nm) | 491 | Em (nm) | 516 | |
| 分子量 | N/A | 溶剂 | Water | |
| 产品详细介绍 | ||||
简要概述
产品基本信息
货号：25580
产品名称：iFluor 488-刀豆蛋白A(ConA)缀合物
规格：1mg
储存条件：-15℃避光防潮
保质期：12个月
产品物理化学光谱特性
Ex(nm)：491
Em(nm)：516
量子产率(cm -1 M -1)：75000
消光系数：0.9
适用仪器
| 荧光显微镜 | |
| 激发： | FITC滤波片 |
| 发射： | FITC滤波片 |
| 推荐孔板： | 黑色透明 |
产品介绍
刀豆蛋白A（ConA）是一种凝集素，它与各种糖、糖蛋白和糖脂中的某些结构特异结合。Con A是一种著名的T细胞有丝分裂原，它能激活免疫系统，募集淋巴细胞并诱导细胞因子的产生。除了有丝分裂活性外，ConA还可以通过线粒体介导的细胞凋亡和自噬诱导细胞程序性死亡。ConA还被报道激活NFAT（活化T细胞的核因子），NFAT是一个转录因子家族，在免疫系统的发育和功能中起重要作用，包括T细胞受体（TCR）的参与。ConA广泛应用于生物学和生物化学中，用来表征细胞表面的糖蛋白和其他含糖物质。还可用于凝集素亲和层析纯化糖基化大分子，以及研究各种免疫细胞的免疫调节作用。ConA在B-聚糖分支结构的末端位置特异性地结合α-D-甘露糖基和α-D-葡萄糖基残基（仅在碳2上的醇中不同的两个己糖）。它有4个结合位点，对应于4个亚单位。刀豆蛋白A（conA）是细胞生物学中应用最广泛的凝集素之一。iFluor 488-刀豆蛋白A(ConA)缀合物选择性地结合到A-甘露吡喃糖基和A-葡萄糖吡喃糖基残基上，发出明亮的绿色荧光。金畔生物是AAT Bioquest的中国代理商，为您提供最优质的iFluor 488-刀豆蛋白A(ConA)缀合物。
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参考文献
A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies.
Authors: Honkanen, Robert A and Huang, Liqun and Rigas, Basil
Journal: Journal of visualized experiments : JoVE (2020)
Acupuncture stimulation attenuates TNF-α production via vagal modulation in the concanavalin A model of hepatitis.
Authors: Lim, Hee-Don and Kim, Ki-Joong and Jo, Byung Gon and Park, Ji-Yeun and Namgung, Uk
Journal: Acupuncture in medicine : journal of the British Medical Acupuncture Society (2020): 964528420907338
Antioxidant Capacity and Hepatoprotective Role of Chitosan-Stabilized Selenium Nanoparticles in Concanavalin A-Induced Liver Injury in Mice.
Authors: Bai, Kaikai and Hong, Bihong and He, Jianlin and Huang, Wenwen
Journal: Nutrients (2020)
Concanavalin A Enhanced Proliferation and Osteogenic Differentiation of Dental Pulp Stem Cells.
Authors: Suardita, Ketut and Arundina, Ira and Tedjosasongko, Udijanto and Yuliati, Anita and Peeters, Harry Huiz and Wijaksana, I Komang Evan and Surboyo, Meircurius Dwi Condro
Journal: European journal of dentistry (2020): 123-127
Concanavalin A Toxicity Towards Potato Psyllid and Apoptosis Induction in Midgut Cells.
Authors: Tang, Xiao-Tian and Ibanez, Freddy and Tamborindeguy, Cecilia
Journal: Insects (2020)
Concanavalin A-Rose Bengal bioconjugate for targeted Gram-negative antimicrobial photodynamic therapy.
Authors: Cantelli, Andrea and Piro, Francesca and Pecchini, Pietro and Di Giosia, Matteo and Danielli, Alberto and Calvaresi, Matteo
Journal: Journal of photochemistry and photobiology. B, Biology (2020): 111852
Deficiency of O-linked-glycosylation regulates activation of T cells and aggravates Concanavalin A-induced liver injury.
Authors: Hao, Xiaohua and Gao, Meixin and He, Lingling and Ye, Xiaohui and Yang, Junru and Zhang, Fuyang and Liu, Ran and Wei, Hongshan
Journal: Toxicology (2020): 152411
Demethyleneberberine attenuates concanavalin A-induced autoimmune hepatitis in mice through inhibition of NF-κB and MAPK signaling.
Authors: Zhang, Miao and Li, Qingxia and Zhou, Cuisong and Zhao, Yaxing and Li, Ruiyan and Zhang, Yubin
Journal: International immunopharmacology (2020): 106137
Developmental exposure to low doses of dichlorodiphenyltrichloroethane impairs proliferative response of thymic lymphocytes to Concanavalin A in rats.
Authors: Yaglova, Nataliya V and Tsomartova, Elina S and Obernikhin, Sergey S and Ivanova, Marina Y and Chereshneva, Elizaveta V and Muhamedova, Svetlana G and Lomanovskaya, Tatiana A and Yaglov, Valentin V
Journal: Heliyon (2020): e03608
ISFET and Dex-AgNPs based portable sensor for reusable and real-time determinations of concanavalin A and glucose on smartphone.
Authors: Zhao, Shuang and Shi, Cong and Hu, Hongyang and Li, Zhengping and Xiao, Gang and Yang, Qiaochun and Sun, Peng and Cheng, Linyang and Niu, Wencheng and Bi, Jinshun and Yue, Zhao
Journal: Biosensors & bioelectronics (2020): 111962