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Dye hydrazides are useful for the labeling of carbonyl compounds like aldehydes and ketones. Many sugars can be converted to carbonyl compounds by periodate oxidation.
Tetramethylrhodamine (TAMRA) is a xanthene fluorophore. This derivative is a pure 5-isomer of TAMRA bearing hydrazide group for the coupling with carbonyl compounds.
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Absorption and emission spectra of 6-TAMRA
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Amine-reactive, activated N-hydroxysuccinimidyl ester of TAMRA dye for the labeling of amine groups of proteins, peptides, and amino-oligonucleotides.
