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Alkyne activated ester for the labeling of amine groups in proteins, peptides and other molecules bearing aliphatic amine functional groups.
Sulfotetrafluorophenyl (STP) esters are excellent alternatives to conventional N-hydroxysuccinimide (NHS) esters. Compared to NHS esters, STP esters provide better ratio of labeling to hydrolysis in aqueous environments.
Hexynoic acid fragment is a short linker with amine. For longer amine linkers, consider using Alkyne-PEG activated esters.
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Recommended protocol
NHS ester labeling of amino biomolecules
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