Thermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应

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hermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应

IL-33 Polyclonal Antibody

Thermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应

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Thermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应

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IL-33 Antibody for Western blot

>> See 3 other antibodies for IL33

Entrez Gene ID:

（Human） 90865

UniProt ID:

O95760

 

Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human （Hu） Murine （Ms） Rat （Rt）
Immunogen: A 19 amino acid peptide from near the center of human IL-33.
Ordering Information
Pierce IL-33 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA5-20398 100 ug Purchase »

Storage: Stored at -20ºC, avoid repeated freeze thaw cycles
Form: 100 ug of affinity chromatography purified antibody （1 mg/ml） in PBS containing 0.02% sodium azide.

 

Applications Dilution *
Western Blot （WB） 1 ug/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

 

Product Specific Information
PA5-20398 targets IL-33 in WB applications and shows reactivity with Human, Murine, and Rat samples.

The PA5-20398 immunogen is a 19 amino acid peptide from near the center of human IL-33.
General Information
Interleukin-33 （IL-33） is a recently identified member of the IL-1 family of cytokines whose other members include IL-1-a/beta, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein （IL-1RAcP）. Receptor binding of IL-33 activates NF-kappa-B and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties.

 

Product Images

Filter : All ApplicationsWB （1 imgs）

 

  • WB using PA5-20398

    Thermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应

    Western Blot with anti-IL-33 Polyclonal Antibody （PA5-20398）

    View Product Details >>

    Western blot analysis of IL-33 in human lymph node tissue lysate with IL-33 antibody at （A） 1 and （B） 2 ug/mL.

    … more >>

     

  • WB using PA5-20398

    Thermo抗体代理IL-33 Polyclonal Antibody Pierce抗体供应

    Western Blot with anti-IL-33 Polyclonal Antibody （PA5-20398）

    View Product Details >>

    Western blot analysis of IL-33 in human lymph node tissue lysate with IL-33 antibody at （A） 1 and （B） 2 ug/mL.

    … more >>

     

 

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