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Hydrazide derivative of Cyanine7, a NIR fluorescent dye, an analog of Cy7®.
This variety of heptamethine fluorophore contains a six-membered ring rigidizing the polymethine chain which allows to increase quantum yield by 20% compared to parent structure.
Hydrazide reacts quickly and smoothly with aldehydes and ketones yielding stable hydrazone products. This reaction is also good for the labeling of glycoproteins after periodate oxidation.
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Cyanine7 absorbance and emission spectra
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